Body mass index is reduced early in Parkinson's Disease

William P. Cheshire; Zbigniew K. Wszolek

doi:10.1016/j.parkreldis.2004.07.001

Body mass index is reduced early in Parkinson's Disease

William P. Cheshire, Zbigniew K. Wszolek

Neurology

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Mean body mass index (BMI) in 100 cases of idiopathic Parkinson's disease (PD) was found to be 9% reduced in comparison to that in patients with either essential tremor or no neurologic disease. A similar reduction in BMI was also discovered among the 24 cases of PD in whom retrospective BMI data were available from their presymptomatic years. These results suggest that alterations in nutrient intake or metabolism could reflect early changes in the central autonomic network preceding the emergence of classical extrapyramidal manifestations of PD.

Original language	English (US)
Pages (from-to)	35-38
Number of pages	4
Journal	Parkinsonism and Related Disorders
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/j.parkreldis.2004.07.001
State	Published - Jan 2005

Keywords

Body mass index
Parkinson's disease
Weight loss

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

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10.1016/j.parkreldis.2004.07.001

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abstract = "Mean body mass index (BMI) in 100 cases of idiopathic Parkinson's disease (PD) was found to be 9% reduced in comparison to that in patients with either essential tremor or no neurologic disease. A similar reduction in BMI was also discovered among the 24 cases of PD in whom retrospective BMI data were available from their presymptomatic years. These results suggest that alterations in nutrient intake or metabolism could reflect early changes in the central autonomic network preceding the emergence of classical extrapyramidal manifestations of PD.",

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AB - Mean body mass index (BMI) in 100 cases of idiopathic Parkinson's disease (PD) was found to be 9% reduced in comparison to that in patients with either essential tremor or no neurologic disease. A similar reduction in BMI was also discovered among the 24 cases of PD in whom retrospective BMI data were available from their presymptomatic years. These results suggest that alterations in nutrient intake or metabolism could reflect early changes in the central autonomic network preceding the emergence of classical extrapyramidal manifestations of PD.

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KW - Weight loss

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Body mass index is reduced early in Parkinson's Disease

Abstract

Keywords

ASJC Scopus subject areas

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