Blood transfusion and risk of non-Hodgkin's lymphoma

Eryn K. Maguire-Boston, Vera Suman, Steve J. Jacobsen, S. Breanndan Moore, Thomas M. Habermann, James R. Cerhan, Aaron R. Folsom

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

A few epidemiologic studies have suggested that blood transfusion may be a risk factor for non-Hodgkin's lymphoma. The authors tested this hypothesis in a population-based, case-control study, using pathologically verified non- Hodgkin's lymphoma cases and transfusion documented via medical records. In 221 age- and sex-matched case-control pairs from Olmsted County, Minnesota, in 1975-1993, the authors observed an odds ratio of 0.84 (95% confidence interval 0.50-1.41) for history of transfusion and non-Hodgkin's lymphoma. There also was no apparent association between transfusion and non-Hodgkin's lymphoma in any subgroup analysis. Results do not support the hypothesis that blood transfusion contributes to the occurrence of non-Hodgkin's lymphoma.

Original languageEnglish (US)
Pages (from-to)1113-1118
Number of pages6
JournalAmerican journal of epidemiology
Volume149
Issue number12
DOIs
StatePublished - Jun 15 1999

Keywords

  • Blood transfusion
  • Case-control studies
  • Lymphoma
  • Non-Hodgkin's

ASJC Scopus subject areas

  • Epidemiology

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