TY - JOUR
T1 - Bladder cancer detection and monitoring
T2 - Assessment of urine- and blood-based marker tests
AU - Goodison, Steve
AU - Rosser, Charles J.
AU - Urquidi, Virginia
N1 - Funding Information:
Acknowledgements The authors are supported in part by research grants from the National Cancer Institute (grant no. RO1 CA116161 [SG]) and the Florida Department of Health James and Esther King Biomedical Program (Team Science Award no. 10KT-01 [CJR] and TTF Award no. IKF06 [SG]). Authors SG and CJR are co-founders and officers of Nonagen Bioscience Corporation. Author VU has no conflict of interest to declare.
PY - 2013/4
Y1 - 2013/4
N2 - Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and management of this disease can be very successful if the disease is detected early. The development of molecular assays that could diagnose bladder cancer accurately, and at an early stage, would be a significant advance. Ideally, such molecular assays would be applicable to non-invasively obtained body fluids, and be designed not only for diagnosis but also for monitoring disease recurrence and response to treatment. In this article, we assess the performance of current diagnostic assays for bladder cancer and discuss some of the emerging biomarkers that could be developed to augment current bladder cancer detection strategies.
AB - Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and management of this disease can be very successful if the disease is detected early. The development of molecular assays that could diagnose bladder cancer accurately, and at an early stage, would be a significant advance. Ideally, such molecular assays would be applicable to non-invasively obtained body fluids, and be designed not only for diagnosis but also for monitoring disease recurrence and response to treatment. In this article, we assess the performance of current diagnostic assays for bladder cancer and discuss some of the emerging biomarkers that could be developed to augment current bladder cancer detection strategies.
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U2 - 10.1007/s40291-013-0023-x
DO - 10.1007/s40291-013-0023-x
M3 - Review article
C2 - 23479428
AN - SCOPUS:84877354258
SN - 1177-1062
VL - 17
SP - 71
EP - 84
JO - Molecular Diagnosis and Therapy
JF - Molecular Diagnosis and Therapy
IS - 2
ER -