Biventricular Involvement In Hypertrophic Cardiomyopathy: Preliminary Analysis Of Cardiac MRIs With Visual Right Ventricular Hypertrophy

Devanshi N. Damani, Anoushka Kapoor, Priyadharshini Sivasubramaniam, Nasibeh Farahani, Moein Enayati, Jeffrey B. Geske, Michael J. Ackerman, Johan M. Bos, Kalyan Pasupathy, Philip A. Araoz, Shivaram P. Arunachalam, Adelaide M. Arruda-Olson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Hypertrophic cardiomyopathy (HCM) is a cardiac muscle disorder known to predominantly affect the left ventricle (LV) of the heart. Recent literature has emphasized the importance of right ventricular abnormalities on clinical outcomes. This study aims to use cardiac magnetic resonance (CMR) imaging to investigate the relationship between left ventricular mass and visually observed right ventricular hypertrophy (RVH) in a large, tertiary care center cohort of patients with HCM spanning 20 years. Out of 1473 patients with HCM who underwent CMR imaging, 852 patients matched the inclusion criteria of the study. 3 trained observers traced the LV and RV contours for these patients using a semi-automated method while simultaneously recording visually appreciated RVH. The data was then analyzed using the t-test to compare the means of the groups. Patients with visually observed RVH had higher LV mass compared to those without RVH (p<0.0001). This correlation persisted in both systole and diastole, regardless of whether papillary muscles were considered a part of the blood pool or the myocardium. Results provide promising preliminary data on the relationship between the LV and RV mass in patients with HCM.

Original languageEnglish (US)
Title of host publicationProceedings - 2022 IEEE 10th International Conference on Healthcare Informatics, ICHI 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages134-137
Number of pages4
ISBN (Electronic)9781665468459
DOIs
StatePublished - 2022
Event10th IEEE International Conference on Healthcare Informatics, ICHI 2022 - Rochester, United States
Duration: Jun 11 2022Jun 14 2022

Publication series

NameProceedings - 2022 IEEE 10th International Conference on Healthcare Informatics, ICHI 2022

Conference

Conference10th IEEE International Conference on Healthcare Informatics, ICHI 2022
Country/TerritoryUnited States
CityRochester
Period6/11/226/14/22

Keywords

  • cardiac magnetic resonance (cmr)
  • hypertrophic cardiomyopathy (hcm)
  • left ventricular hypertrophy (lvh)
  • right ventricular hypertrophy (rvh)

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Science Applications
  • Information Systems and Management
  • Safety, Risk, Reliability and Quality
  • Health Informatics

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