BiPAP in acute respiratory failure due to myasthenic crisis may prevent intubation

Alejandro Rabinstein, Eelco F.M. Wijdicks

Research output: Contribution to journalArticle

83 Scopus citations

Abstract

Noninvasive mechanical ventilation using bilevel positive pressure ventilation (BiPAP) has not been studied in acute respiratory failure caused by MG. Eleven episodes in nine patients were initially managed with BiPAP, and endotracheal intubation was avoided in seven of these trials. Presence of hypercapnia (PaCO2 greater than 50 mm Hg) at onset predicted BiPAP failure and subsequent intubation. Results of this preliminary study suggest that a trial of BiPAP may prevent intubation in patients with myasthenic crisis without overt hypercapnia.

Original languageEnglish (US)
Pages (from-to)1647-1649
Number of pages3
JournalNeurology
Volume59
Issue number10
DOIs
StatePublished - Nov 26 2002

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'BiPAP in acute respiratory failure due to myasthenic crisis may prevent intubation'. Together they form a unique fingerprint.

  • Cite this