Bioprinting a cardiac valve

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Heart valve tissue engineering could be a possible solution for the limitations of mechanical and biological prostheses, which are commonly used for heart valve replacement. In tissue engineering, cells are seeded into a 3-dimensional platform, termed the scaffold, to make the engineered tissue construct. However, mimicking the mechanical and spatial heterogeneity of a heart valve structure in a fabricated scaffold with uniform cell distribution is daunting when approached conventionally. Bioprinting is an emerging technique that can produce biological products containing matrix and cells, together or separately with morphological, structural and mechanical diversity. This advance increases the possibility of fabricating the structure of a heart valve in vitro and using it as a functional tissue construct for implantation. This review describes the use of bioprinting technology in heart valve tissue engineering.

Original languageEnglish (US)
JournalBiotechnology Advances
DOIs
StateAccepted/In press - Jan 15 2015

Fingerprint

Bioprinting
Heart Valves
Tissue Engineering
Tissue engineering
Scaffolds
Tissue
Prosthetics
Biological Products
Prostheses and Implants
Technology

Keywords

  • 2-Dimensional printing
  • 3-Dimensional printing
  • Bioprinting
  • Heart valve
  • Hydrogel

ASJC Scopus subject areas

  • Biotechnology

Cite this

Bioprinting a cardiac valve. / Jana, Soumen; Lerman, Amir.

In: Biotechnology Advances, 15.01.2015.

Research output: Contribution to journalArticle

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