Biomarkers and diagnostic tools for detection of Helicobacter pylori

Akbar Khalilpour, Mehdi Kazemzadeh-Narbat, Ali Tamayol, Rahmi Oklu, Ali Khademhosseini

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.

Original languageEnglish (US)
Pages (from-to)4723-4734
Number of pages12
JournalApplied Microbiology and Biotechnology
Volume100
Issue number11
DOIs
StatePublished - Jun 1 2016

Fingerprint

Helicobacter pylori
Biomarkers
Immunologic Tests
Microfluidics
Helicobacter Infections
Bacterial Infections
Stomach Neoplasms
Economics
Morbidity
Mortality
Infection
Population

Keywords

  • Diagnostic kits
  • Helicobacter pylori
  • Infection markers
  • Microfluidic systems

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Khalilpour, A., Kazemzadeh-Narbat, M., Tamayol, A., Oklu, R., & Khademhosseini, A. (2016). Biomarkers and diagnostic tools for detection of Helicobacter pylori. Applied Microbiology and Biotechnology, 100(11), 4723-4734. https://doi.org/10.1007/s00253-016-7495-7

Biomarkers and diagnostic tools for detection of Helicobacter pylori. / Khalilpour, Akbar; Kazemzadeh-Narbat, Mehdi; Tamayol, Ali; Oklu, Rahmi; Khademhosseini, Ali.

In: Applied Microbiology and Biotechnology, Vol. 100, No. 11, 01.06.2016, p. 4723-4734.

Research output: Contribution to journalReview article

Khalilpour, A, Kazemzadeh-Narbat, M, Tamayol, A, Oklu, R & Khademhosseini, A 2016, 'Biomarkers and diagnostic tools for detection of Helicobacter pylori', Applied Microbiology and Biotechnology, vol. 100, no. 11, pp. 4723-4734. https://doi.org/10.1007/s00253-016-7495-7
Khalilpour, Akbar ; Kazemzadeh-Narbat, Mehdi ; Tamayol, Ali ; Oklu, Rahmi ; Khademhosseini, Ali. / Biomarkers and diagnostic tools for detection of Helicobacter pylori. In: Applied Microbiology and Biotechnology. 2016 ; Vol. 100, No. 11. pp. 4723-4734.
@article{5a29f43ae8dc49d3b42519ce3489e56d,
title = "Biomarkers and diagnostic tools for detection of Helicobacter pylori",
abstract = "Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.",
keywords = "Diagnostic kits, Helicobacter pylori, Infection markers, Microfluidic systems",
author = "Akbar Khalilpour and Mehdi Kazemzadeh-Narbat and Ali Tamayol and Rahmi Oklu and Ali Khademhosseini",
year = "2016",
month = "6",
day = "1",
doi = "10.1007/s00253-016-7495-7",
language = "English (US)",
volume = "100",
pages = "4723--4734",
journal = "Applied Microbiology and Biotechnology",
issn = "0175-7598",
publisher = "Springer Verlag",
number = "11",

}

TY - JOUR

T1 - Biomarkers and diagnostic tools for detection of Helicobacter pylori

AU - Khalilpour, Akbar

AU - Kazemzadeh-Narbat, Mehdi

AU - Tamayol, Ali

AU - Oklu, Rahmi

AU - Khademhosseini, Ali

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.

AB - Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.

KW - Diagnostic kits

KW - Helicobacter pylori

KW - Infection markers

KW - Microfluidic systems

UR - http://www.scopus.com/inward/record.url?scp=84963749779&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84963749779&partnerID=8YFLogxK

U2 - 10.1007/s00253-016-7495-7

DO - 10.1007/s00253-016-7495-7

M3 - Review article

C2 - 27084783

AN - SCOPUS:84963749779

VL - 100

SP - 4723

EP - 4734

JO - Applied Microbiology and Biotechnology

JF - Applied Microbiology and Biotechnology

SN - 0175-7598

IS - 11

ER -