Biomarkers and diagnostic tools for detection of Helicobacter pylori

Akbar Khalilpour, Mehdi Kazemzadeh-Narbat, Ali Tamayol, Rahmi Oklu, Ali Khademhosseini

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.

Original languageEnglish (US)
Pages (from-to)4723-4734
Number of pages12
JournalApplied Microbiology and Biotechnology
Volume100
Issue number11
DOIs
StatePublished - Jun 1 2016

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Keywords

  • Diagnostic kits
  • Helicobacter pylori
  • Infection markers
  • Microfluidic systems

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Khalilpour, A., Kazemzadeh-Narbat, M., Tamayol, A., Oklu, R., & Khademhosseini, A. (2016). Biomarkers and diagnostic tools for detection of Helicobacter pylori. Applied Microbiology and Biotechnology, 100(11), 4723-4734. https://doi.org/10.1007/s00253-016-7495-7