Biology of T lymphocytes

Abbe N. Vallejo; Eduardo Davila; Cornelia M. Weyand; Jörg J. Goronzy

doi:10.1016/S0889-857X(03)00114-5

Biology of T lymphocytes

Abbe N. Vallejo, Eduardo Davila, Cornelia M. Weyand, Jörg J. Goronzy

Immunology

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

The biology of T cells is reviewed. T-cell ontogeny, differentiation of effector functions, tolerance, memory, senescence, and the cellular and molecular mechanisms that regulate T-cell mediated immune responses are discussed with consideration to their applicability to human disease pathogenesis. As appropriate, new paradigms or paradigm shifts are presented.

Original language	English (US)
Pages (from-to)	135-157
Number of pages	23
Journal	Rheumatic Disease Clinics of North America
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/S0889-857X(03)00114-5
State	Published - Feb 2004

ASJC Scopus subject areas

Rheumatology

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10.1016/S0889-857X(03)00114-5

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title = "Biology of T lymphocytes",

abstract = "The biology of T cells is reviewed. T-cell ontogeny, differentiation of effector functions, tolerance, memory, senescence, and the cellular and molecular mechanisms that regulate T-cell mediated immune responses are discussed with consideration to their applicability to human disease pathogenesis. As appropriate, new paradigms or paradigm shifts are presented.",

author = "Vallejo, {Abbe N.} and Eduardo Davila and Weyand, {Cornelia M.} and Goronzy, {J{\"o}rg J.}",

note = "Funding Information: Supported by grants from the National Institutes of Health (R01 AG22379, R01 AG15043, R01 AR41974, R01 AI44142, R01 AR42527, R01 EY11916, and R01 HL63919) and by the Mayo Foundation. ",

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doi = "10.1016/S0889-857X(03)00114-5",

language = "English (US)",

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T1 - Biology of T lymphocytes

AU - Vallejo, Abbe N.

AU - Davila, Eduardo

AU - Weyand, Cornelia M.

AU - Goronzy, Jörg J.

N1 - Funding Information: Supported by grants from the National Institutes of Health (R01 AG22379, R01 AG15043, R01 AR41974, R01 AI44142, R01 AR42527, R01 EY11916, and R01 HL63919) and by the Mayo Foundation.

PY - 2004/2

Y1 - 2004/2

N2 - The biology of T cells is reviewed. T-cell ontogeny, differentiation of effector functions, tolerance, memory, senescence, and the cellular and molecular mechanisms that regulate T-cell mediated immune responses are discussed with consideration to their applicability to human disease pathogenesis. As appropriate, new paradigms or paradigm shifts are presented.

AB - The biology of T cells is reviewed. T-cell ontogeny, differentiation of effector functions, tolerance, memory, senescence, and the cellular and molecular mechanisms that regulate T-cell mediated immune responses are discussed with consideration to their applicability to human disease pathogenesis. As appropriate, new paradigms or paradigm shifts are presented.

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DO - 10.1016/S0889-857X(03)00114-5

M3 - Review article

C2 - 15061572

AN - SCOPUS:1242300055

SN - 0889-857X

VL - 30

SP - 135

EP - 157

JO - Rheumatic Disease Clinics of North America

JF - Rheumatic Disease Clinics of North America

IS - 1

ER -

Biology of T lymphocytes

Abstract

ASJC Scopus subject areas

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