Biological reductionism versus redundancy in a degenerate world

Michael Joseph Joyner, Laszlo G. Boros, Gregory Fink

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The precision medicine narrative relies on the reductionist assumption that there is a strong linkage between genotype and complex traits (phenotypes). This essay uses examples from humans and other “higher” animals to argue that redundant and degenerate mechanisms operating at the physiological level limit both the general utility of this assumption and the specific utility of the precision medicine narrative.

Original languageEnglish (US)
Pages (from-to)517-526
Number of pages10
JournalPerspectives in Biology and Medicine
Volume61
Issue number4
DOIs
StatePublished - Sep 1 2018

ASJC Scopus subject areas

  • Issues, ethics and legal aspects
  • Health Policy
  • History and Philosophy of Science

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