Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus

Michael J. Yaszemski; Antonios G. Mikos; Richard G. Payne; Wilson C. Hayes

Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus

Michael J. Yaszemski, Antonios G. Mikos, Richard G. Payne, Wilson C. Hayes

Orthopedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

Our laboratory has been developing a particulate composite material as a temporary replacement for trabecular bone. The material is degradable in physiologic fluids, and uses starting materials that the body can metabolize and excrete. This study investigates the influence of the molecular weight of one component, a linear polyester, on the mechanical strength of the composite material. The compressive strength and modulus increase from `low' to `medium' molecular weight, but do not increase further from `medium' to `high' molecular weight. Low, medium, and high are relative to the highest molecular weight attainable with the current reaction scheme, which is a number average molecular weight (M_n) of 2,038 and a weight average molecular weight (M_w) of 11,916.

Original language	English (US)
Title of host publication	Materials Research Society Symposium Proceedings
Publisher	Publ by Materials Research Society
Pages	251-255
Number of pages	5
ISBN (Print)	1558992308
State	Published - 1994
Event	Proceedings of the Biomaterials for Drug and Cell Delivery - Boston, MA, USA Duration: Nov 29 1993 → Dec 1 1993

Publication series

Name	Materials Research Society Symposium Proceedings
Volume	331
ISSN (Print)	0272-9172

Other

Other	Proceedings of the Biomaterials for Drug and Cell Delivery
City	Boston, MA, USA
Period	11/29/93 → 12/1/93

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

Cite this

Yaszemski, M. J., Mikos, A. G., Payne, R. G., & Hayes, W. C. (1994). Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. In Materials Research Society Symposium Proceedings (pp. 251-255). (Materials Research Society Symposium Proceedings; Vol. 331). Publ by Materials Research Society.

Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. / Yaszemski, Michael J.; Mikos, Antonios G.; Payne, Richard G. et al.
Materials Research Society Symposium Proceedings. Publ by Materials Research Society, 1994. p. 251-255 (Materials Research Society Symposium Proceedings; Vol. 331).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yaszemski, MJ, Mikos, AG, Payne, RG & Hayes, WC 1994, Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. in Materials Research Society Symposium Proceedings. Materials Research Society Symposium Proceedings, vol. 331, Publ by Materials Research Society, pp. 251-255, Proceedings of the Biomaterials for Drug and Cell Delivery, Boston, MA, USA, 11/29/93.

Yaszemski, Michael J. ; Mikos, Antonios G. ; Payne, Richard G. et al. / Biodegradable polymer composites for temporary replacement of trabecular bone : the effect of polymer molecular weight on composite strength and modulus. Materials Research Society Symposium Proceedings. Publ by Materials Research Society, 1994. pp. 251-255 (Materials Research Society Symposium Proceedings).

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AB - Our laboratory has been developing a particulate composite material as a temporary replacement for trabecular bone. The material is degradable in physiologic fluids, and uses starting materials that the body can metabolize and excrete. This study investigates the influence of the molecular weight of one component, a linear polyester, on the mechanical strength of the composite material. The compressive strength and modulus increase from `low' to `medium' molecular weight, but do not increase further from `medium' to `high' molecular weight. Low, medium, and high are relative to the highest molecular weight attainable with the current reaction scheme, which is a number average molecular weight (Mn) of 2,038 and a weight average molecular weight (Mw) of 11,916.

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Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus

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