Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus

Michael J Yaszemski, Antonios G. Mikos, Richard G. Payne, Wilson C. Hayes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

Our laboratory has been developing a particulate composite material as a temporary replacement for trabecular bone. The material is degradable in physiologic fluids, and uses starting materials that the body can metabolize and excrete. This study investigates the influence of the molecular weight of one component, a linear polyester, on the mechanical strength of the composite material. The compressive strength and modulus increase from `low' to `medium' molecular weight, but do not increase further from `medium' to `high' molecular weight. Low, medium, and high are relative to the highest molecular weight attainable with the current reaction scheme, which is a number average molecular weight (Mn) of 2,038 and a weight average molecular weight (Mw) of 11,916.

Original languageEnglish (US)
Title of host publicationMaterials Research Society Symposium Proceedings
Place of PublicationPittsburgh, PA, United States
PublisherPubl by Materials Research Society
Pages251-255
Number of pages5
Volume331
ISBN (Print)1558992308
StatePublished - 1994
Externally publishedYes
EventProceedings of the Biomaterials for Drug and Cell Delivery - Boston, MA, USA
Duration: Nov 29 1993Dec 1 1993

Other

OtherProceedings of the Biomaterials for Drug and Cell Delivery
CityBoston, MA, USA
Period11/29/9312/1/93

Fingerprint

Biodegradable polymers
bone
Polymers
Bone
polymer
replacement
Molecular weight
Composite materials
Polyesters
Compressive strength
Strength of materials
effect
compressive strength
Fluids
fluid
material

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Engineering(all)
  • Earth and Planetary Sciences(all)
  • Environmental Science(all)

Cite this

Yaszemski, M. J., Mikos, A. G., Payne, R. G., & Hayes, W. C. (1994). Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. In Materials Research Society Symposium Proceedings (Vol. 331, pp. 251-255). Pittsburgh, PA, United States: Publ by Materials Research Society.

Biodegradable polymer composites for temporary replacement of trabecular bone : the effect of polymer molecular weight on composite strength and modulus. / Yaszemski, Michael J; Mikos, Antonios G.; Payne, Richard G.; Hayes, Wilson C.

Materials Research Society Symposium Proceedings. Vol. 331 Pittsburgh, PA, United States : Publ by Materials Research Society, 1994. p. 251-255.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yaszemski, MJ, Mikos, AG, Payne, RG & Hayes, WC 1994, Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. in Materials Research Society Symposium Proceedings. vol. 331, Publ by Materials Research Society, Pittsburgh, PA, United States, pp. 251-255, Proceedings of the Biomaterials for Drug and Cell Delivery, Boston, MA, USA, 11/29/93.
Yaszemski MJ, Mikos AG, Payne RG, Hayes WC. Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. In Materials Research Society Symposium Proceedings. Vol. 331. Pittsburgh, PA, United States: Publ by Materials Research Society. 1994. p. 251-255
Yaszemski, Michael J ; Mikos, Antonios G. ; Payne, Richard G. ; Hayes, Wilson C. / Biodegradable polymer composites for temporary replacement of trabecular bone : the effect of polymer molecular weight on composite strength and modulus. Materials Research Society Symposium Proceedings. Vol. 331 Pittsburgh, PA, United States : Publ by Materials Research Society, 1994. pp. 251-255
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