Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus

Michael J. Yaszemski, Antonios G. Mikos, Richard G. Payne, Wilson C. Hayes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Our laboratory has been developing a particulate composite material as a temporary replacement for trabecular bone. The material is degradable in physiologic fluids, and uses starting materials that the body can metabolize and excrete. This study investigates the influence of the molecular weight of one component, a linear polyester, on the mechanical strength of the composite material. The compressive strength and modulus increase from `low' to `medium' molecular weight, but do not increase further from `medium' to `high' molecular weight. Low, medium, and high are relative to the highest molecular weight attainable with the current reaction scheme, which is a number average molecular weight (Mn) of 2,038 and a weight average molecular weight (Mw) of 11,916.

Original languageEnglish (US)
Title of host publicationMaterials Research Society Symposium Proceedings
PublisherPubl by Materials Research Society
Pages251-255
Number of pages5
ISBN (Print)1558992308
StatePublished - Jan 1 1994
EventProceedings of the Biomaterials for Drug and Cell Delivery - Boston, MA, USA
Duration: Nov 29 1993Dec 1 1993

Publication series

NameMaterials Research Society Symposium Proceedings
Volume331
ISSN (Print)0272-9172

Other

OtherProceedings of the Biomaterials for Drug and Cell Delivery
CityBoston, MA, USA
Period11/29/9312/1/93

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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    Yaszemski, M. J., Mikos, A. G., Payne, R. G., & Hayes, W. C. (1994). Biodegradable polymer composites for temporary replacement of trabecular bone: the effect of polymer molecular weight on composite strength and modulus. In Materials Research Society Symposium Proceedings (pp. 251-255). (Materials Research Society Symposium Proceedings; Vol. 331). Publ by Materials Research Society.