Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

Timothy L. Kline; Yun Hao Xu; Ying Jing; Jian Ping Wang

doi:10.1016/j.jmmm.2009.02.079

Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

Timothy L. Kline, Yun Hao Xu, Ying Jing, Jian Ping Wang

Radiology

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory.

Original language	English (US)
Pages (from-to)	1525-1528
Number of pages	4
Journal	Journal of Magnetism and Magnetic Materials
Volume	321
Issue number	10
DOIs	https://doi.org/10.1016/j.jmmm.2009.02.079
State	Published - May 2009

Keywords

Au shell
Cancer treatment
Core-shell
High-moment
Hyperthermia
Magnetic fluid
Nanoparticles
Physical vapor deposition
Specific absorption rate
Tumor cell

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics

Access to Document

10.1016/j.jmmm.2009.02.079

Cite this

@article{be1ea585753a48229edef7d041a6714f,

title = "Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization",

abstract = "A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory.",

keywords = "Au shell, Cancer treatment, Core-shell, High-moment, Hyperthermia, Magnetic fluid, Nanoparticles, Physical vapor deposition, Specific absorption rate, Tumor cell",

author = "Kline, {Timothy L.} and Xu, {Yun Hao} and Ying Jing and Wang, {Jian Ping}",

note = "Funding Information: The authors would like to thank the National Science Foundation for part of the financial support for this work under grant NSF BME 075345 and the Institute of Engineering in Medicine through the Medical Device Center at the University of Minnesota. Also, for help with the Dynamic Light Scattering measurements, we thank Pengyun Zeng in the Pharmacy Department at the University of Minnesota. We also thank the help of Prof. Andy Taton and Dr. Ying Zhang of Chemistry Department, University of Minnesota. Copyright: Copyright 2012 Elsevier B.V., All rights reserved.",

year = "2009",

month = may,

doi = "10.1016/j.jmmm.2009.02.079",

language = "English (US)",

volume = "321",

pages = "1525--1528",

journal = "Journal of Magnetism and Magnetic Materials",

issn = "0304-8853",

publisher = "Elsevier",

number = "10",

}

TY - JOUR

T1 - Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

AU - Kline, Timothy L.

AU - Xu, Yun Hao

AU - Jing, Ying

AU - Wang, Jian Ping

N1 - Funding Information: The authors would like to thank the National Science Foundation for part of the financial support for this work under grant NSF BME 075345 and the Institute of Engineering in Medicine through the Medical Device Center at the University of Minnesota. Also, for help with the Dynamic Light Scattering measurements, we thank Pengyun Zeng in the Pharmacy Department at the University of Minnesota. We also thank the help of Prof. Andy Taton and Dr. Ying Zhang of Chemistry Department, University of Minnesota. Copyright: Copyright 2012 Elsevier B.V., All rights reserved.

PY - 2009/5

Y1 - 2009/5

N2 - A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory.

AB - A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory.

KW - Au shell

KW - Cancer treatment

KW - Core-shell

KW - High-moment

KW - Hyperthermia

KW - Magnetic fluid

KW - Nanoparticles

KW - Physical vapor deposition

KW - Specific absorption rate

KW - Tumor cell

UR - http://www.scopus.com/inward/record.url?scp=64249089911&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=64249089911&partnerID=8YFLogxK

U2 - 10.1016/j.jmmm.2009.02.079

DO - 10.1016/j.jmmm.2009.02.079

M3 - Article

AN - SCOPUS:64249089911

SN - 0304-8853

VL - 321

SP - 1525

EP - 1528

JO - Journal of Magnetism and Magnetic Materials

JF - Journal of Magnetism and Magnetic Materials

IS - 10

ER -

Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this