Biocompatible high-moment FeCo-Au magnetic nanoparticles for magnetic hyperthermia treatment optimization

Timothy L. Kline, Yun Hao Xu, Ying Jing, Jian Ping Wang

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

A great deal of attention has been paid to the use of magnetite nanoparticles as heating elements in the research of magnetic fluid hyperthermia. However, these particles have a relatively low magnetization and as a result, have low heating efficiency as well as difficulties in detection applications. To maximize heating efficiency we propose and show the use of high-moment Fe(Co)-Au core-shell nanoparticles. Using a physical vapor nanoparticle-deposition technique the high-moment nanoparticles were synthesized. The water-soluble particles were placed in an AC magnetic field of variable magnetic field frequencies. The temperature rise was measured and compared to theory.

Original languageEnglish (US)
Pages (from-to)1525-1528
Number of pages4
JournalJournal of Magnetism and Magnetic Materials
Volume321
Issue number10
DOIs
StatePublished - May 1 2009

Keywords

  • Au shell
  • Cancer treatment
  • Core-shell
  • High-moment
  • Hyperthermia
  • Magnetic fluid
  • Nanoparticles
  • Physical vapor deposition
  • Specific absorption rate
  • Tumor cell

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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