Abstract
Cholangiocytes, the cells lining the bile ducts, are now recognized as important contributors to and modulators of bile formation. During the last few years, remarkable insights have been made into the mechanisms of fluid, electrolyte, and solute transport by biliary epithelia, as well as increasing knowledge of the complex endocrine, paracrine, and neurologic factors regulating bile formation. Advances in the past year include an increased understanding of the interaction between bile acids and cholangiocytes in the regulation of bile formation in normal and cholestatic states and greater insight into the pathogenic mechanisms of biliary diseases. References to recent comprehensive reviews of specific areas of biliary physiology are provided, and new experimental models are also described.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 432-436 |
| Number of pages | 5 |
| Journal | Current Opinion in Gastroenterology |
| Volume | 16 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2000 |
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ASJC Scopus subject areas
- Gastroenterology
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Biliary tract physiology. / Prall, Richard T.; La Russo, Nicholas F.
In: Current Opinion in Gastroenterology, Vol. 16, No. 5, 2000, p. 432-436.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biliary tract physiology
AU - Prall, Richard T.
AU - La Russo, Nicholas F
PY - 2000
Y1 - 2000
N2 - Cholangiocytes, the cells lining the bile ducts, are now recognized as important contributors to and modulators of bile formation. During the last few years, remarkable insights have been made into the mechanisms of fluid, electrolyte, and solute transport by biliary epithelia, as well as increasing knowledge of the complex endocrine, paracrine, and neurologic factors regulating bile formation. Advances in the past year include an increased understanding of the interaction between bile acids and cholangiocytes in the regulation of bile formation in normal and cholestatic states and greater insight into the pathogenic mechanisms of biliary diseases. References to recent comprehensive reviews of specific areas of biliary physiology are provided, and new experimental models are also described.
AB - Cholangiocytes, the cells lining the bile ducts, are now recognized as important contributors to and modulators of bile formation. During the last few years, remarkable insights have been made into the mechanisms of fluid, electrolyte, and solute transport by biliary epithelia, as well as increasing knowledge of the complex endocrine, paracrine, and neurologic factors regulating bile formation. Advances in the past year include an increased understanding of the interaction between bile acids and cholangiocytes in the regulation of bile formation in normal and cholestatic states and greater insight into the pathogenic mechanisms of biliary diseases. References to recent comprehensive reviews of specific areas of biliary physiology are provided, and new experimental models are also described.
UR - http://www.scopus.com/inward/record.url?scp=0034456871&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034456871&partnerID=8YFLogxK
U2 - 10.1097/00001574-200009000-00008
DO - 10.1097/00001574-200009000-00008
M3 - Article
C2 - 17031116
AN - SCOPUS:0034456871
VL - 16
SP - 432
EP - 436
JO - Current Opinion in Gastroenterology
JF - Current Opinion in Gastroenterology
SN - 0267-1379
IS - 5
ER -