Bile acids: An underrecognized and underappreciated cause of chronic diarrhea

Raful Sameer Islam, John K. Di Baise

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Bile acid malabsorption is a common cause of chronic watery diarrhea; however, its role appears to be poorly appreciated among clinicians. As such, bile acid diarrhea remains an underrecognized cause of chronic diarrhea, resulting in many patients incorrectly diagnosed and interfering and delaying proper treatment. In this review, we briefy discuss the synthesis, enterohepatic circulation, and function of bile acids. We then focus on the role of bile acids in bile acid malabsorption including the diagnostic and treatment options. By recognizing that bile acid malabsorption is a relatively common cause of chronic diarrhea, we hope that more physicians will more effectively evaluate and treat patients with this condition.

Original languageEnglish (US)
Pages (from-to)32-44
Number of pages13
JournalPractical Gastroenterology
Volume36
Issue number10
StatePublished - Oct 2012

Fingerprint

Bile Acids and Salts
Diarrhea
Enterohepatic Circulation
Physicians
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Bile acids : An underrecognized and underappreciated cause of chronic diarrhea. / Islam, Raful Sameer; Di Baise, John K.

In: Practical Gastroenterology, Vol. 36, No. 10, 10.2012, p. 32-44.

Research output: Contribution to journalArticle

Islam, Raful Sameer ; Di Baise, John K. / Bile acids : An underrecognized and underappreciated cause of chronic diarrhea. In: Practical Gastroenterology. 2012 ; Vol. 36, No. 10. pp. 32-44.
@article{50412e9a33174531aeedfcbbe81c8d21,
title = "Bile acids: An underrecognized and underappreciated cause of chronic diarrhea",
abstract = "Bile acid malabsorption is a common cause of chronic watery diarrhea; however, its role appears to be poorly appreciated among clinicians. As such, bile acid diarrhea remains an underrecognized cause of chronic diarrhea, resulting in many patients incorrectly diagnosed and interfering and delaying proper treatment. In this review, we briefy discuss the synthesis, enterohepatic circulation, and function of bile acids. We then focus on the role of bile acids in bile acid malabsorption including the diagnostic and treatment options. By recognizing that bile acid malabsorption is a relatively common cause of chronic diarrhea, we hope that more physicians will more effectively evaluate and treat patients with this condition.",
author = "Islam, {Raful Sameer} and {Di Baise}, {John K.}",
year = "2012",
month = "10",
language = "English (US)",
volume = "36",
pages = "32--44",
journal = "Practical Gastroenterology",
issn = "0277-4208",
publisher = "Shugar Publishing Inc.",
number = "10",

}

TY - JOUR

T1 - Bile acids

T2 - An underrecognized and underappreciated cause of chronic diarrhea

AU - Islam, Raful Sameer

AU - Di Baise, John K.

PY - 2012/10

Y1 - 2012/10

N2 - Bile acid malabsorption is a common cause of chronic watery diarrhea; however, its role appears to be poorly appreciated among clinicians. As such, bile acid diarrhea remains an underrecognized cause of chronic diarrhea, resulting in many patients incorrectly diagnosed and interfering and delaying proper treatment. In this review, we briefy discuss the synthesis, enterohepatic circulation, and function of bile acids. We then focus on the role of bile acids in bile acid malabsorption including the diagnostic and treatment options. By recognizing that bile acid malabsorption is a relatively common cause of chronic diarrhea, we hope that more physicians will more effectively evaluate and treat patients with this condition.

AB - Bile acid malabsorption is a common cause of chronic watery diarrhea; however, its role appears to be poorly appreciated among clinicians. As such, bile acid diarrhea remains an underrecognized cause of chronic diarrhea, resulting in many patients incorrectly diagnosed and interfering and delaying proper treatment. In this review, we briefy discuss the synthesis, enterohepatic circulation, and function of bile acids. We then focus on the role of bile acids in bile acid malabsorption including the diagnostic and treatment options. By recognizing that bile acid malabsorption is a relatively common cause of chronic diarrhea, we hope that more physicians will more effectively evaluate and treat patients with this condition.

UR - http://www.scopus.com/inward/record.url?scp=84868228667&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868228667&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84868228667

VL - 36

SP - 32

EP - 44

JO - Practical Gastroenterology

JF - Practical Gastroenterology

SN - 0277-4208

IS - 10

ER -