Bilateral temporal bone langerhans cell histiocytosis: radiologic pearls

Mira A. Coleman, Jane Matsumoto, Carrie Carr, Laurence J. Eckel, Amulya A. Nageswara Rao

Research output: Contribution to journalArticle

Abstract

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is exceedingly rare. Furthermore, LCH is commonly misinterpreted as mastoiditis, otitis media and otitis externa, delaying diagnosis and appropriate therapeutic management. To improve detection and time to treatment, it is imperative to have LCH in the differential diagnosis for unusual presentations of the aforementioned infectious head and neck etiologies. Any lytic lesion of the temporal bone identified by radiology should raise suspicion for LCH. We hereby describe the radiologic findings of a case of bilateral temporal bone LCH, originally misdiagnosed as mastoiditis.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalThe open neuroimaging journal
Volume7
DOIs
StatePublished - Jan 1 2013

Fingerprint

Langerhans Cell Histiocytosis
Temporal Bone
Mastoiditis
Neck
Head
Otitis Externa
Otitis Media
Diagnostic Errors
Radiology
Differential Diagnosis

Keywords

  • Bilateral temporal bone
  • CT
  • Langerhans cell histiocytosis
  • Mastoiditis
  • MRI.

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Bilateral temporal bone langerhans cell histiocytosis : radiologic pearls. / Coleman, Mira A.; Matsumoto, Jane; Carr, Carrie; Eckel, Laurence J.; Nageswara Rao, Amulya A.

In: The open neuroimaging journal, Vol. 7, 01.01.2013, p. 53-57.

Research output: Contribution to journalArticle

Coleman, Mira A. ; Matsumoto, Jane ; Carr, Carrie ; Eckel, Laurence J. ; Nageswara Rao, Amulya A. / Bilateral temporal bone langerhans cell histiocytosis : radiologic pearls. In: The open neuroimaging journal. 2013 ; Vol. 7. pp. 53-57.
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