TY - JOUR
T1 - Big Data and comparative effectiveness research in radiation oncology
T2 - Synergy and accelerated discovery
AU - Trifiletti, Daniel M.
AU - Showalter, Timothy N.
N1 - Publisher Copyright:
© 2015 Trifiletti and Showalter.
PY - 2015
Y1 - 2015
N2 - Several advances in large data set collection and processing have the potential to provide a wave of new insights and improvements in the use of radiation therapy for cancer treatment. The era of electronic health records, genomics, and improving information technology resources creates the opportunity to leverage these developments to create a learning healthcare system that can rapidly deliver informative clinical evidence. By merging concepts from comparative effectiveness research with the tools and analytic approaches of "big data," it is hoped that this union will accelerate discovery, improve evidence for decision making, and increase the availability of highly relevant, personalized information. This combination offers the potential to provide data and analysis that can be leveraged for ultra-personalized medicine and high-quality, cutting-edge radiation therapy.
AB - Several advances in large data set collection and processing have the potential to provide a wave of new insights and improvements in the use of radiation therapy for cancer treatment. The era of electronic health records, genomics, and improving information technology resources creates the opportunity to leverage these developments to create a learning healthcare system that can rapidly deliver informative clinical evidence. By merging concepts from comparative effectiveness research with the tools and analytic approaches of "big data," it is hoped that this union will accelerate discovery, improve evidence for decision making, and increase the availability of highly relevant, personalized information. This combination offers the potential to provide data and analysis that can be leveraged for ultra-personalized medicine and high-quality, cutting-edge radiation therapy.
KW - Big data
KW - CER
KW - EMR
KW - Effectiveness
KW - Gene
KW - Radiation
UR - http://www.scopus.com/inward/record.url?scp=84954469853&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84954469853&partnerID=8YFLogxK
U2 - 10.3389/fonc.2015.00274
DO - 10.3389/fonc.2015.00274
M3 - Article
AN - SCOPUS:84954469853
SN - 2234-943X
VL - 5
JO - Frontiers in Oncology
JF - Frontiers in Oncology
IS - DEC
M1 - 274
ER -