Abstract
Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 400-407 |
| Number of pages | 8 |
| Journal | International Journal of Cardiology |
| Volume | 201 |
| DOIs | |
| State | Published - Oct 10 2015 |
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Keywords
- Aortic aneurysm
- Aortic dissection
- Bicuspid aortic valve
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Bicuspid aortic valve aortopathy in adults : Incidence, etiology, and clinical significance. / Michelena, Hector I; Corte, Alessandro Della; Prakash, Siddharth K.; Milewicz, Dianna M.; Evangelista, Artur; Sarano, Maurice E.
In: International Journal of Cardiology, Vol. 201, 10.10.2015, p. 400-407.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bicuspid aortic valve aortopathy in adults
T2 - Incidence, etiology, and clinical significance
AU - Michelena, Hector I
AU - Corte, Alessandro Della
AU - Prakash, Siddharth K.
AU - Milewicz, Dianna M.
AU - Evangelista, Artur
AU - Sarano, Maurice E
PY - 2015/10/10
Y1 - 2015/10/10
N2 - Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.
AB - Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.
KW - Aortic aneurysm
KW - Aortic dissection
KW - Bicuspid aortic valve
UR - http://www.scopus.com/inward/record.url?scp=84943551099&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84943551099&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2015.08.106
DO - 10.1016/j.ijcard.2015.08.106
M3 - Article
C2 - 26310986
AN - SCOPUS:84943551099
VL - 201
SP - 400
EP - 407
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -