Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Hector I Michelena; Alessandro Della Corte; Siddharth K. Prakash; Dianna M. Milewicz; Artur Evangelista; Maurice E Sarano

doi:10.1016/j.ijcard.2015.08.106

Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Hector I Michelena, Alessandro Della Corte, Siddharth K. Prakash, Dianna M. Milewicz, Artur Evangelista, Maurice E Sarano

Cardiovascular Medicine

Research output: Contribution to journal › Article

56 Scopus citations

Abstract

Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

Original language	English (US)
Pages (from-to)	400-407
Number of pages	8
Journal	International Journal of Cardiology
Volume	201
DOIs	https://doi.org/10.1016/j.ijcard.2015.08.106
State	Published - Oct 10 2015

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Keywords

Aortic aneurysm
Aortic dissection
Bicuspid aortic valve

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

Michelena, H. I., Corte, A. D., Prakash, S. K., Milewicz, D. M., Evangelista, A., & Sarano, M. E. (2015). Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance. International Journal of Cardiology, 201, 400-407. https://doi.org/10.1016/j.ijcard.2015.08.106

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10.1016/j.ijcard.2015.08.106