Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Hector I. Michelena; Alessandro Della Corte; Siddharth K. Prakash; Dianna M. Milewicz; Artur Evangelista; Maurice Enriquez-Sarano

doi:10.1016/j.ijcard.2015.08.106

Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Hector I. Michelena, Alessandro Della Corte, Siddharth K. Prakash, Dianna M. Milewicz, Artur Evangelista, Maurice Enriquez-Sarano

Cardiovascular Medicine

Research output: Contribution to journal › Review article › peer-review

76 Scopus citations

Abstract

Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

Original language	English (US)
Pages (from-to)	400-407
Number of pages	8
Journal	International Journal of Cardiology
Volume	201
DOIs	https://doi.org/10.1016/j.ijcard.2015.08.106
State	Published - Oct 10 2015

Keywords

Aortic aneurysm
Aortic dissection
Bicuspid aortic valve

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.ijcard.2015.08.106

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Bicuspid aortic valve aortopathy in adults : Incidence, etiology, and clinical significance. / Michelena, Hector I.; Corte, Alessandro Della; Prakash, Siddharth K.; Milewicz, Dianna M.; Evangelista, Artur; Enriquez-Sarano, Maurice.

In: International Journal of Cardiology, Vol. 201, 10.10.2015, p. 400-407.

Research output: Contribution to journal › Review article › peer-review

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abstract = "Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.",

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AU - Corte, Alessandro Della

AU - Prakash, Siddharth K.

AU - Milewicz, Dianna M.

AU - Evangelista, Artur

AU - Enriquez-Sarano, Maurice

PY - 2015/10/10

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N2 - Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

AB - Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

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KW - Aortic dissection

KW - Bicuspid aortic valve

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Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Abstract

Keywords

ASJC Scopus subject areas

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