Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Hector I Michelena; Alessandro Della Corte; Siddharth K. Prakash; Dianna M. Milewicz; Artur Evangelista; Maurice E Sarano

doi:10.1016/j.ijcard.2015.08.106

Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance

Hector I Michelena, Alessandro Della Corte, Siddharth K. Prakash, Dianna M. Milewicz, Artur Evangelista, Maurice E Sarano

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

Original language	English (US)
Pages (from-to)	400-407
Number of pages	8
Journal	International Journal of Cardiology
Volume	201
DOIs	https://doi.org/10.1016/j.ijcard.2015.08.106
State	Published - Oct 10 2015

Keywords

Aortic aneurysm
Aortic dissection
Bicuspid aortic valve

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.ijcard.2015.08.106

Fingerprint Dive into the research topics of 'Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance'. Together they form a unique fingerprint.

Cite this

@article{eac2d5f6705e4a4baf5ad225366757e1,

title = "Bicuspid aortic valve aortopathy in adults: Incidence, etiology, and clinical significance",

abstract = "Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.",

keywords = "Aortic aneurysm, Aortic dissection, Bicuspid aortic valve",

author = "Michelena, {Hector I} and Corte, {Alessandro Della} and Prakash, {Siddharth K.} and Milewicz, {Dianna M.} and Artur Evangelista and Sarano, {Maurice E}",

year = "2015",

month = oct,

day = "10",

doi = "10.1016/j.ijcard.2015.08.106",

language = "English (US)",

volume = "201",

pages = "400--407",

journal = "International Journal of Cardiology",

issn = "0167-5273",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Bicuspid aortic valve aortopathy in adults

T2 - Incidence, etiology, and clinical significance

AU - Michelena, Hector I

AU - Corte, Alessandro Della

AU - Prakash, Siddharth K.

AU - Milewicz, Dianna M.

AU - Evangelista, Artur

AU - Sarano, Maurice E

PY - 2015/10/10

Y1 - 2015/10/10

N2 - Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

AB - Bicuspid aortic valve is the most common congenital heart defect and is associated with an aortopathy manifested by dilatation of the ascending thoracic aorta. The clinical consequences of this aortopathy are the need for periodic monitoring of aortic diameters, elective prophylactic surgical aortic repair, and the occurrence of aortic dissection or rupture. This review describes the current knowledge of BAV aortopathy in adults, including incidence, pathophysiologic insights into its etiology, contemporary hypothesis-generating observations into its complications, and recommendations for monitoring and intervention.

KW - Aortic aneurysm

KW - Aortic dissection

KW - Bicuspid aortic valve

UR - http://www.scopus.com/inward/record.url?scp=84943551099&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84943551099&partnerID=8YFLogxK

U2 - 10.1016/j.ijcard.2015.08.106

DO - 10.1016/j.ijcard.2015.08.106

M3 - Article

C2 - 26310986

AN - SCOPUS:84943551099

VL - 201

SP - 400

EP - 407

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

ER -