Bell's palsy preceding Parkinson's disease: A case-control study

Rodolfo Savica, James Howard Bower, Demetrius M. Maraganore, Brandon R. Grossardt, Walter A Rocca

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We investigated the association of Bell's palsy (BP) with the subsequent risk of Parkinson's disease (PD) using a case-control study design. We matched 196 incident cases of PD in Olmsted County, MN, to 196 general population controls with same age (±1 year) and sex, and we reviewed the complete medical records of cases and controls in a medical records-linkage system to detect BP. Six of the 196 patients with PD and none of the 196 controls were diagnosed with BP before PD (exact binomial probability, P = 0.02). The median age at occurrence of BP was 49.5 years (range, 15-84 years) and the median time between BP and the onset of PD was 27.5 years (range, 2-54 years). The findings were similar using a standardized incidence ratio (SIR) approach, but were not statistically significant. This initial association between BP and PD awaits replication.

Original languageEnglish (US)
Pages (from-to)1530-1533
Number of pages4
JournalMovement Disorders
Volume24
Issue number10
DOIs
StatePublished - Jul 30 2009

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Bell Palsy
Parkinson Disease
Case-Control Studies
Medical Record Linkage
Population Control
Medical Records
Incidence

Keywords

  • Bell's palsy
  • Case-control study
  • Parkinson's disease
  • Risk factors

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Bell's palsy preceding Parkinson's disease : A case-control study. / Savica, Rodolfo; Bower, James Howard; Maraganore, Demetrius M.; Grossardt, Brandon R.; Rocca, Walter A.

In: Movement Disorders, Vol. 24, No. 10, 30.07.2009, p. 1530-1533.

Research output: Contribution to journalArticle

Savica, Rodolfo ; Bower, James Howard ; Maraganore, Demetrius M. ; Grossardt, Brandon R. ; Rocca, Walter A. / Bell's palsy preceding Parkinson's disease : A case-control study. In: Movement Disorders. 2009 ; Vol. 24, No. 10. pp. 1530-1533.
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