Bell's palsy preceding Parkinson's disease: A case-control study

Rodolfo Savica, James H. Bower, Demetrius M. Maraganore, Brandon R. Grossardt, Walter A. Rocca

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We investigated the association of Bell's palsy (BP) with the subsequent risk of Parkinson's disease (PD) using a case-control study design. We matched 196 incident cases of PD in Olmsted County, MN, to 196 general population controls with same age (±1 year) and sex, and we reviewed the complete medical records of cases and controls in a medical records-linkage system to detect BP. Six of the 196 patients with PD and none of the 196 controls were diagnosed with BP before PD (exact binomial probability, P = 0.02). The median age at occurrence of BP was 49.5 years (range, 15-84 years) and the median time between BP and the onset of PD was 27.5 years (range, 2-54 years). The findings were similar using a standardized incidence ratio (SIR) approach, but were not statistically significant. This initial association between BP and PD awaits replication.

Original languageEnglish (US)
Pages (from-to)1530-1533
Number of pages4
JournalMovement Disorders
Volume24
Issue number10
DOIs
StatePublished - Jul 30 2009

Keywords

  • Bell's palsy
  • Case-control study
  • Parkinson's disease
  • Risk factors

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Bell's palsy preceding Parkinson's disease: A case-control study'. Together they form a unique fingerprint.

  • Cite this