Behavioral Symptoms in Long-Term Survivors of Ischemic Stroke

Beth K Rush, Rebecca B. McNeil, Dale M. Gamble, Sothear H. Luke, Alexa N. Richie, Colleen S. Albers, Robert D Jr. Brown, Thomas G Brott, James F Meschia

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The range of behavioral changes occurring after stroke has not yet been fully characterized. To evaluate behavioral symptoms after stroke and clinical characteristics that may influence the number and frequency of such symptoms, we compared 53 survivors of mild ischemic stroke with 30 stroke-free controls. Stroke survivor and control participants completed self-ratings of behavioral symptoms and were administered measures of cognitive status (ie, Beck Depression Inventory II, Mini-Mental State Examination, and Controlled Oral Word Association Test). Informants of stroke survivors and controls completed ratings of behavioral symptoms and functional status (ie, Neuropsychiatric Inventory Questionnaire, Informant Questionnaire on Cognitive Decline in the Elderly, and Functional Activities Questionnaire). More behavioral symptoms were observed in stroke survivors than in controls (mean [standard deviation] total number of symptoms on the Neuropsychiatric Inventory Questionnaire, 2.1 [2.0] vs 1.1 [1.5]; P = .02). Informants of stroke survivors were more likely to recognize behavioral symptoms than were stroke survivors themselves. Higher initial stroke severity was associated with more behavioral symptoms. With more behavioral symptoms, there was more functional impairment. Our findings suggest that behavioral symptoms can have unique and troublesome effects on stroke patients. Future research is needed to understand how the identification of behavioral symptoms after stroke can improve care in stroke survivors.

Original languageEnglish (US)
Pages (from-to)326-332
Number of pages7
JournalJournal of Stroke and Cerebrovascular Diseases
Volume19
Issue number4
DOIs
StatePublished - Jul 2010

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Behavioral Symptoms
Survivors
Stroke
Equipment and Supplies
Word Association Tests
Oral Diagnosis

Keywords

  • Cerebral stroke
  • long-term effects
  • neurobehavioral manifestations

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Rehabilitation
  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Cite this

Behavioral Symptoms in Long-Term Survivors of Ischemic Stroke. / Rush, Beth K; McNeil, Rebecca B.; Gamble, Dale M.; Luke, Sothear H.; Richie, Alexa N.; Albers, Colleen S.; Brown, Robert D Jr.; Brott, Thomas G; Meschia, James F.

In: Journal of Stroke and Cerebrovascular Diseases, Vol. 19, No. 4, 07.2010, p. 326-332.

Research output: Contribution to journalArticle

Rush, Beth K ; McNeil, Rebecca B. ; Gamble, Dale M. ; Luke, Sothear H. ; Richie, Alexa N. ; Albers, Colleen S. ; Brown, Robert D Jr. ; Brott, Thomas G ; Meschia, James F. / Behavioral Symptoms in Long-Term Survivors of Ischemic Stroke. In: Journal of Stroke and Cerebrovascular Diseases. 2010 ; Vol. 19, No. 4. pp. 326-332.
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