BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer

Christopher D. Koch, Amy M. Wockenfus, Amy K. Saenger, Allan S. Jaffe, Brad S. Karon

Research output: Contribution to journalArticle

15 Scopus citations


Objectives: In an attempt to reduce false positive results and improve turnaround time, we investigated the BD Rapid Serum Tube as an alternate sample type to lithium heparin plasma for Roche Troponin T analysis on the Roche Cobas e411 analyzer. Design and methods: BD Plasma Separator Tubes (PST) and Rapid Serum Tubes (RST) were collected in tandem from Emergency Department patients who had clinical orders for Troponin T over a 1. month period. Results: RST and PST samples yielded analytically and clinically concordant Troponin T results on the Roche Cobas e411. Rare false positive results in lithium heparin samples were not observed with rapid clot serum tubes. Conclusions: RST samples are appropriate for stat Troponin T analysis, and appear to reduce the incidence of rare false positive Troponin T results obtained with lithium heparin samples.

Original languageEnglish (US)
Pages (from-to)842-844
Number of pages3
JournalClinical Biochemistry
Issue number10-11
StatePublished - Jul 1 2012



  • Rapid serum tube
  • Troponin t

ASJC Scopus subject areas

  • Clinical Biochemistry

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