BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer

Christopher D. Koch, Amy M. Wockenfus, Amy K. Saenger, Allan S Jaffe, Brad S. Karon

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objectives: In an attempt to reduce false positive results and improve turnaround time, we investigated the BD Rapid Serum Tube as an alternate sample type to lithium heparin plasma for Roche Troponin T analysis on the Roche Cobas e411 analyzer. Design and methods: BD Plasma Separator Tubes (PST) and Rapid Serum Tubes (RST) were collected in tandem from Emergency Department patients who had clinical orders for Troponin T over a 1. month period. Results: RST and PST samples yielded analytically and clinically concordant Troponin T results on the Roche Cobas e411. Rare false positive results in lithium heparin samples were not observed with rapid clot serum tubes. Conclusions: RST samples are appropriate for stat Troponin T analysis, and appear to reduce the incidence of rare false positive Troponin T results obtained with lithium heparin samples.

Original languageEnglish (US)
Pages (from-to)842-844
Number of pages3
JournalClinical Biochemistry
Volume45
Issue number10-11
DOIs
StatePublished - Jul 2012

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Troponin T
Plasmas
Lithium
Heparin
Serum
Separators
Turnaround time
Hospital Emergency Service
Incidence

Keywords

  • Rapid serum tube
  • Troponin t

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer. / Koch, Christopher D.; Wockenfus, Amy M.; Saenger, Amy K.; Jaffe, Allan S; Karon, Brad S.

In: Clinical Biochemistry, Vol. 45, No. 10-11, 07.2012, p. 842-844.

Research output: Contribution to journalArticle

Koch, Christopher D. ; Wockenfus, Amy M. ; Saenger, Amy K. ; Jaffe, Allan S ; Karon, Brad S. / BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer. In: Clinical Biochemistry. 2012 ; Vol. 45, No. 10-11. pp. 842-844.
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