Basic fibroblast growth factor increases cortical blood flow in vivo

Luca Regli; Robert E. Anderson; Fredric B. Meyer

doi:10.1016/0006-8993(94)91167-3

Basic fibroblast growth factor increases cortical blood flow in vivo

Luca Regli, Robert E. Anderson, Fredric B. Meyer

Neurosurgery

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Basic FGF has recently been shown to produce systemic and cerebral vasodilation. To test the hypothesis that _bFGF increases regional cortical blood flow (rCBF), rCBF and brain pH_i were measured while _bFGF or vehicle was superperfused onto the cortex of rabbits. The results of this study demonstrate that topical application of _bFGF causes an increase in rCBF.

Original language	English (US)
Pages (from-to)	155-157
Number of pages	3
Journal	Brain Research
Volume	665
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(94)91167-3
State	Published - Nov 28 1994

Keywords

Basic fibroblast growth factor
Brain pH
Regional cortical blood flow

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(94)91167-3

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title = "Basic fibroblast growth factor increases cortical blood flow in vivo",

abstract = "Basic FGF has recently been shown to produce systemic and cerebral vasodilation. To test the hypothesis that bFGF increases regional cortical blood flow (rCBF), rCBF and brain pHi were measured while bFGF or vehicle was superperfused onto the cortex of rabbits. The results of this study demonstrate that topical application of bFGF causes an increase in rCBF.",

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year = "1994",

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AU - Regli, Luca

AU - Anderson, Robert E.

AU - Meyer, Fredric B.

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N2 - Basic FGF has recently been shown to produce systemic and cerebral vasodilation. To test the hypothesis that bFGF increases regional cortical blood flow (rCBF), rCBF and brain pHi were measured while bFGF or vehicle was superperfused onto the cortex of rabbits. The results of this study demonstrate that topical application of bFGF causes an increase in rCBF.

AB - Basic FGF has recently been shown to produce systemic and cerebral vasodilation. To test the hypothesis that bFGF increases regional cortical blood flow (rCBF), rCBF and brain pHi were measured while bFGF or vehicle was superperfused onto the cortex of rabbits. The results of this study demonstrate that topical application of bFGF causes an increase in rCBF.

KW - Basic fibroblast growth factor

KW - Brain pH

KW - Regional cortical blood flow

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Basic fibroblast growth factor increases cortical blood flow in vivo

Abstract

Keywords

ASJC Scopus subject areas

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