Abstract
A 62-year-old woman presented with episodic sweating and shivering with reduced core temperature. Brain MRI demonstrated a basal forebrain malformation. Physiologic testing included EEG, SPECT, heat challenge, and autonomic testing. Glycopyrrolate aborted spells and raised core temperature. Hypothalamic dysregulation is likely the primary pathophysiology in the setting of other forebrain anomalies. These findings expand the structural abnormalities and treatment options within the temperature dysregulating conditions of Shapiro's syndrome and "diencephalic epilepsy".
| Original language | English (US) |
|---|---|
| Pages (from-to) | 254-256 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 56 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 23 2001 |
ASJC Scopus subject areas
- Clinical Neurology
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Klein, C. J., Silber, M. H., Halliwill, J. R., Schreiner, S. A., Suarez, G. A., & Low, P. A. (2001). Basal forebrain malformation with hyperhidrosis and hypothermia: Variant of Shapiro's syndrome. Neurology, 56(2), 254-256. https://doi.org/10.1212/WNL.56.2.254