Balance between sympathetic response to head-up tilt and cardiac vagal factors in healthy humans

Farah A. Ramírez-Marrero; Nisha Charkoudian; Liu Zhong; Christiane Hesse; John H. Eisenach

doi:10.1007/s10286-007-0427-y

Balance between sympathetic response to head-up tilt and cardiac vagal factors in healthy humans

Farah A. Ramírez-Marrero, Nisha Charkoudian, Liu Zhong, Christiane Hesse, John H. Eisenach

Anesthesiology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We evaluated the association between cardio-vagal baroreflex sensitivity (BRS; assessed with modified Oxford technique) and catecholamine response to 5 min 60° head-up tilt (HUT) in 46 young healthy adults. HUT increased HR, mean arterial pressure, and NE (P < 0.05 for all). BRS was negatively correlated with NE response to HUT (r = -0.36, P < 0.05), suggesting that subjects with high vagal modulation (high BRS) require less sympathetic response (NE) to maintain normotension during orthostatic stress.

Original language	English (US)
Pages (from-to)	227-230
Number of pages	4
Journal	Clinical Autonomic Research
Volume	17
Issue number	4
DOIs	https://doi.org/10.1007/s10286-007-0427-y
State	Published - Jun 2007

Keywords

Baroreflex
Norepinephrine
Orthostatic
Tilt-table test

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Clinical Neurology

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10.1007/s10286-007-0427-y

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abstract = "We evaluated the association between cardio-vagal baroreflex sensitivity (BRS; assessed with modified Oxford technique) and catecholamine response to 5 min 60° head-up tilt (HUT) in 46 young healthy adults. HUT increased HR, mean arterial pressure, and NE (P < 0.05 for all). BRS was negatively correlated with NE response to HUT (r = -0.36, P < 0.05), suggesting that subjects with high vagal modulation (high BRS) require less sympathetic response (NE) to maintain normotension during orthostatic stress.",

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AU - Ramírez-Marrero, Farah A.

AU - Charkoudian, Nisha

AU - Zhong, Liu

AU - Hesse, Christiane

AU - Eisenach, John H.

PY - 2007/6

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AB - We evaluated the association between cardio-vagal baroreflex sensitivity (BRS; assessed with modified Oxford technique) and catecholamine response to 5 min 60° head-up tilt (HUT) in 46 young healthy adults. HUT increased HR, mean arterial pressure, and NE (P < 0.05 for all). BRS was negatively correlated with NE response to HUT (r = -0.36, P < 0.05), suggesting that subjects with high vagal modulation (high BRS) require less sympathetic response (NE) to maintain normotension during orthostatic stress.

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KW - Norepinephrine

KW - Orthostatic

KW - Tilt-table test

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Balance between sympathetic response to head-up tilt and cardiac vagal factors in healthy humans

Abstract

Keywords

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