Balance between sympathetic response to head-up tilt and cardiac vagal factors in healthy humans

Farah A. Ramírez-Marrero, Nisha Charkoudian, Liu Zhong, Christiane Hesse, John H. Eisenach

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We evaluated the association between cardio-vagal baroreflex sensitivity (BRS; assessed with modified Oxford technique) and catecholamine response to 5 min 60° head-up tilt (HUT) in 46 young healthy adults. HUT increased HR, mean arterial pressure, and NE (P < 0.05 for all). BRS was negatively correlated with NE response to HUT (r = -0.36, P < 0.05), suggesting that subjects with high vagal modulation (high BRS) require less sympathetic response (NE) to maintain normotension during orthostatic stress.

Original languageEnglish (US)
Pages (from-to)227-230
Number of pages4
JournalClinical Autonomic Research
Volume17
Issue number4
DOIs
StatePublished - Jun 1 2007

Keywords

  • Baroreflex
  • Norepinephrine
  • Orthostatic
  • Tilt-table test

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology

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