Autonomic function and unmyelinated fibers in chronic inflammatory demyelinating polyradiculonuropathy

Timothy J. Ingall, James G. McLeod, Naotoshi Tamura

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Because autonomic function may be abnormal in some demyelinating peripheral neuropathies, it has been studied with a number of noninvasive and invasive tests in 14 patients with chronic inflammatory demyelinating polyradiculoneuropathy. There were abnormalities of the 30:15 ratio in 3 patients and an abnormal thermoregulatory sweat test in 5 patients. These findings are indicative of mild parasympathetic and sympathetic dysfunction. Minor pathological changes in unmyelinated fibers were demonstrated on morphometric examination of sural nerves of 10 patients.

Original languageEnglish (US)
Pages (from-to)70-76
Number of pages7
JournalMuscle & Nerve
Volume13
Issue number1
DOIs
StatePublished - Jan 1990

Keywords

  • autonomic function tests
  • autonomic nerves system
  • chronic inflammatory neuropathy
  • sural nerve pathology
  • unmyelinated fibers

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

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