Autoimmune Pancreatitis: How to Recognize This Entity and Avoid Surgical Treatment

Raghuwansh P. Sah, Suresh T Chari

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Autoimmune pancreatitis (AIP) is a rare disease with a presentation mimics that of pancreatic cancer. It is exquisitely responsive to steroids. Unnecessary operative intervention can be avoided with a correct and timely diagnosis of AIP. In contrast, because pancreatic cancer is relatively more common, there is a risk of misdiagnosing pancreatic cancer as AIP, which has grave clinical consequences. International consensus diagnostic criteria (ICDC) for diagnosing AIP have been established. These criteria are based on features of pancreatic imaging, serum immunoglobulin G4 (IgG4) levels, other organ involvement, pancreatic histology, and response to steroid treatment. A careful diagnostic approach using the ICDC allows diagnosis of AIP and differentiating it from pancreatic cancer.

Original languageEnglish (US)
Title of host publicationPancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management
PublisherWiley Blackwell
Pages364-372
Number of pages9
ISBN (Electronic)9781118307816
ISBN (Print)9780470673188
DOIs
StatePublished - Apr 7 2015

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Keywords

  • Autoimmune pancreatitis
  • Idiopathic duct-centric pancreatitis
  • IgG4
  • Lymphoplasmacytic sclerosing pancreatitis
  • Pancreatic cancer

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sah, R. P., & Chari, S. T. (2015). Autoimmune Pancreatitis: How to Recognize This Entity and Avoid Surgical Treatment. In Pancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management (pp. 364-372). Wiley Blackwell. https://doi.org/10.1002/9781118307816.ch51