Autoimmune pancreatitis: an update

Ashish Khandelwal, Dai Inoue, Naoki Takahashi

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Objective: Since the time of inception of autoimmune pancreatitis (AIP), our knowledge of autoimmune pancreatitis has expanded significantly. The aim of this review is to provide an update on clinical manifestations, diagnosis, imaging features, and treatment of AIP. Background and clinical significance: Type 1 AIP is the pancreatic manifestation of IgG4-related systemic disease, which can be diagnosed using a combination of clinical, histopathological, pancreatic imaging findings in conjunction with manifestation in other organs, as well of responsiveness to steroid treatment. It is vital to differentiate AIP from pancreatic cancer since both can mimic each other clinically and radiologically. Type 2 AIP is a rare but distinct subtype of AIP which occurs mostly in the younger patient. Conclusion: AIP is steroid-responsive chronic pancreatitis with distinct manifestations on imaging.

Original languageEnglish (US)
Pages (from-to)1359-1370
Number of pages12
JournalAbdominal Radiology
Volume45
Issue number5
DOIs
StatePublished - May 1 2020

Keywords

  • Autoimmune pancreatitis
  • Idiopathic duct-centric pancreatitis
  • IgG4
  • International consensus diagnostic criteria
  • Lymphoplasmacytic sclerosing pancreatitis

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

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