Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil

Patompong Ungprasert, V. R. Chowdhary, M. D. Davis, Ashima Makol

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Hematological abnormalities, such as anemia, leucopenia, and thrombocytopenia, secondary to peripheral destruction, are common in systemic lupus erythematosus (SLE). However, cytopenias from autoimmune myelofibrosis (AIMF) are extremely uncommon in SLE, with less than 40 reported cases in the literature. We report the case of a 33-year-old female who presented with bullous skin lesions and pancytopenia as the presenting manifestation of what was ultimately diagnosed as SLE with AIMF. She responded well to glucocorticoids and mycophenolate mofetil.

Original languageEnglish (US)
Pages (from-to)427-430
Number of pages4
JournalLupus
Volume25
Issue number4
DOIs
StatePublished - Apr 1 2016

Fingerprint

Mycophenolic Acid
Primary Myelofibrosis
Pancytopenia
Systemic Lupus Erythematosus
Leukopenia
Blister
Thrombocytopenia
Glucocorticoids
Anemia
Skin

Keywords

  • cutaneous lupus
  • hematologic changes
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology

Cite this

Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil. / Ungprasert, Patompong; Chowdhary, V. R.; Davis, M. D.; Makol, Ashima.

In: Lupus, Vol. 25, No. 4, 01.04.2016, p. 427-430.

Research output: Contribution to journalArticle

@article{aa412045eb4f4883ac7c50fc3d5c3d39,
title = "Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil",
abstract = "Hematological abnormalities, such as anemia, leucopenia, and thrombocytopenia, secondary to peripheral destruction, are common in systemic lupus erythematosus (SLE). However, cytopenias from autoimmune myelofibrosis (AIMF) are extremely uncommon in SLE, with less than 40 reported cases in the literature. We report the case of a 33-year-old female who presented with bullous skin lesions and pancytopenia as the presenting manifestation of what was ultimately diagnosed as SLE with AIMF. She responded well to glucocorticoids and mycophenolate mofetil.",
keywords = "cutaneous lupus, hematologic changes, Systemic lupus erythematosus",
author = "Patompong Ungprasert and Chowdhary, {V. R.} and Davis, {M. D.} and Ashima Makol",
year = "2016",
month = "4",
day = "1",
doi = "10.1177/0961203315615221",
language = "English (US)",
volume = "25",
pages = "427--430",
journal = "Lupus",
issn = "0961-2033",
publisher = "SAGE Publications Ltd",
number = "4",

}

TY - JOUR

T1 - Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil

AU - Ungprasert, Patompong

AU - Chowdhary, V. R.

AU - Davis, M. D.

AU - Makol, Ashima

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Hematological abnormalities, such as anemia, leucopenia, and thrombocytopenia, secondary to peripheral destruction, are common in systemic lupus erythematosus (SLE). However, cytopenias from autoimmune myelofibrosis (AIMF) are extremely uncommon in SLE, with less than 40 reported cases in the literature. We report the case of a 33-year-old female who presented with bullous skin lesions and pancytopenia as the presenting manifestation of what was ultimately diagnosed as SLE with AIMF. She responded well to glucocorticoids and mycophenolate mofetil.

AB - Hematological abnormalities, such as anemia, leucopenia, and thrombocytopenia, secondary to peripheral destruction, are common in systemic lupus erythematosus (SLE). However, cytopenias from autoimmune myelofibrosis (AIMF) are extremely uncommon in SLE, with less than 40 reported cases in the literature. We report the case of a 33-year-old female who presented with bullous skin lesions and pancytopenia as the presenting manifestation of what was ultimately diagnosed as SLE with AIMF. She responded well to glucocorticoids and mycophenolate mofetil.

KW - cutaneous lupus

KW - hematologic changes

KW - Systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=84960441019&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84960441019&partnerID=8YFLogxK

U2 - 10.1177/0961203315615221

DO - 10.1177/0961203315615221

M3 - Article

C2 - 26537421

AN - SCOPUS:84960441019

VL - 25

SP - 427

EP - 430

JO - Lupus

JF - Lupus

SN - 0961-2033

IS - 4

ER -