Autoimmune Limbic Encephalitis

Shahar Shelly, Ram Narayan, Divyanshu Dubey

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Autoimmune encephalitis is now being widely recognized as a common and potentially treatable cause of encephalitis. The majority of the autoimmune encephalitis cases clinically present with limbic system dysfunction. Many neural autoantibody biomarkers of autoimmune limbic encephalitis have been described, and novel antibodies are being recognized every year. These antibodies are either directed against cell surface epitopes or intracellular antigens. Learning about the specific clinical presentations of autoimmune encephalitides, their pathophysiology, and cancer association is crucial for patient care. We highlight the typical clinical and radiological features of autoimmune limbic encephalitides. We also describe the treatment strategies and immunotherapy agents utilized.

Original languageEnglish (US)
Title of host publicationContemporary Clinical Neuroscience
PublisherSpringer Nature
Pages567-597
Number of pages31
DOIs
StatePublished - 2019

Publication series

NameContemporary Clinical Neuroscience
ISSN (Print)2627-535X
ISSN (Electronic)2627-5341

Keywords

  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis
  • Antibodies
  • Immunotherapy
  • Limbic Encephalitis
  • Paraneoplastic Syndromes

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Neurology
  • Sensory Systems
  • Clinical Neurology

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