Autoimmune hemolytic anemia in a patient with autosomal dominant chronic mucocutaneous candidiasis

David P. Steensma, Ayalew Tefferi, Catherine R. Weiler

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Chronic mucocutaneous candidiasis is a heterogeneous immunodeficiency syndrome characterized by recurrent candidal infections of the skin, nails, and mucous membranes. The syndrome can be associated with autoimmune conditions, especially endocrine disorders. Typically, inheritance is autosomal recessive, and abnormal T-cell-mediated immunity is thought to be the underlying deficit. We describe a 27-year-old man with chronic mucocutaneous candidiasis inherited in an autosomal dominant fashion, in whom both lymphocyte blastogenesis and delayed-type skin reactivity to Candida antigens were normal. Notable features of the case include autoimmune hemolytic anemia, probable hypoparathyroidism, and hypogonadal hypogonadism.

Original languageEnglish (US)
Pages (from-to)853-855
Number of pages3
JournalMayo Clinic Proceedings
Volume75
Issue number8
StatePublished - 2000

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Chronic Mucocutaneous Candidiasis
Autoimmune Hemolytic Anemia
Hypoparathyroidism
Skin
Hypogonadism
Lymphocyte Activation
Nails
Candida
Cellular Immunity
Mucous Membrane
Lymphocytes
T-Lymphocytes
Antigens
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Autoimmune hemolytic anemia in a patient with autosomal dominant chronic mucocutaneous candidiasis. / Steensma, David P.; Tefferi, Ayalew; Weiler, Catherine R.

In: Mayo Clinic Proceedings, Vol. 75, No. 8, 2000, p. 853-855.

Research output: Contribution to journalArticle

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