Autism Spectrum Disorder: Incidence and Time Trends Over Two Decades in a Population-Based Birth Cohort

Scott M. Myers, Robert G. Voigt, Robert C. Colligan, Amy L. Weaver, Curtis B. Storlie, Ruth E. Stoeckel, John D. Port, Slavica K. Katusic

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

We retrospectively identified autism spectrum disorder (ASD) incident cases among 31,220 individuals in a population-based birth cohort based on signs and symptoms uniformly abstracted from medical and educational records. Inclusive and narrow research definitions of ASD (ASD-R I and ASD-R N , respectively) were explored, along with clinical diagnoses of ASD (ASD-C) obtained from the records. The incidence of ASD-R I, ASD-R N , and ASD-C increased significantly from 1985 to 1998, then ASD-R I and ASD-R N plateaued while the rate of ASD-C continued to increase during 1998–2004. The rising incidence of research-defined ASD may reflect improved recognition and documentation of ASD signs and symptoms. Although the frequency of threshold ASD symptoms stabilized, the rate of ASD-C continued to increase, narrowing the gap between clinical ascertainment and symptom documentation.

Original languageEnglish (US)
Pages (from-to)1455-1474
Number of pages20
JournalJournal of Autism and Developmental Disorders
Volume49
Issue number4
DOIs
StatePublished - Apr 1 2019

Keywords

  • Autism spectrum disorder
  • Epidemiology
  • Incidence
  • Time trends

ASJC Scopus subject areas

  • Developmental and Educational Psychology

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