Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats

Ee Hwa Kim, Younhee Kim, Mi-Hyeon D Jang, Baek Vin Lim, Youn Jung Kim, Joo Ho Chung, Chang Ju Kim

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The aim of the present study was to investigate whether stimulation of auricular acupuncture point has any effects on the expression of neuropeptide Y (NPY), appetite-inducing factor particularly abundant in the mammalian hypothalamus. In food-deprived condition, enhanced NPY expression was detected in both the arcuate nucleus (ARN) and the paraventricular nucleus (PVN) of the hypothalamus via immunohistochemistry in Sprague-Dawley rats. Needling the unfed rats on the auricular point resulted in decreased NPY levels in both the ARN and PVN, while it increased NPY levels in the ARN and PVN of fed rats. The present findings indicate that auricular acupuncture may affect NPY expression in the ARN and PVN of the hypothalamus.

Original languageEnglish (US)
Pages (from-to)113-116
Number of pages4
JournalNeuroscience Letters
Volume307
Issue number2
DOIs
StatePublished - Jul 13 2001
Externally publishedYes

Fingerprint

Ear Acupuncture
Neuropeptide Y
Arcuate Nucleus of Hypothalamus
Paraventricular Hypothalamic Nucleus
Hypothalamus
Sprague Dawley Rats
Food
Acupuncture Points
Appetite
Immunohistochemistry

Keywords

  • Arcuate nucleus
  • Auricular acupuncture
  • Food intake
  • Hypothalamus
  • Immunohistochemistry
  • Neuropeptide Y
  • Paraventricular nucleus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats. / Kim, Ee Hwa; Kim, Younhee; Jang, Mi-Hyeon D; Lim, Baek Vin; Kim, Youn Jung; Chung, Joo Ho; Kim, Chang Ju.

In: Neuroscience Letters, Vol. 307, No. 2, 13.07.2001, p. 113-116.

Research output: Contribution to journalArticle

Kim, Ee Hwa ; Kim, Younhee ; Jang, Mi-Hyeon D ; Lim, Baek Vin ; Kim, Youn Jung ; Chung, Joo Ho ; Kim, Chang Ju. / Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats. In: Neuroscience Letters. 2001 ; Vol. 307, No. 2. pp. 113-116.
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