Auranofin-associated colitis and eosinophilia

Research output: Contribution to journalArticle

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Abstract

Gold compounds, often used in the treatment of rheumatoid arthritis, have been associated with gastrointestinal disturbances in some patients. Use of auranofin, an oral gold preparation, in a 50-year-old woman with rheumatoid arthritis resulted in diarrhea, abdominal tenderness, nausea, and vomiting, which persisted despite discontinuation of auranofin therapy. The presumptive diagnosis was gold-induced colitis and eosinophila. Administration of cromolyn sodium provided relief. Although this complication may be rare, evolving bowel symptoms in patients receiving auranofin demand prompt attention.

Original languageEnglish (US)
Pages (from-to)142-144
Number of pages3
JournalMayo Clinic Proceedings
Volume62
Issue number2
StatePublished - 1987

Fingerprint

Auranofin
Eosinophilia
Colitis
Gold
Rheumatoid Arthritis
Gold Compounds
Cromolyn Sodium
Nausea
Vomiting
Diarrhea
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Auranofin-associated colitis and eosinophilia. / Michet, Clement; Rakela, Jorge; Luthra, H. S.

In: Mayo Clinic Proceedings, Vol. 62, No. 2, 1987, p. 142-144.

Research output: Contribution to journalArticle

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