Auranofin-Associated Colitis and Eosinophilia

CLEMENT J. MICHET, JORGE RAKELA, HARVINDER S. LUTHRA

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Gold compounds, often used in the treatment of rheumatoid arthritis, have been associated with gastrointestinal disturbances in some patients. Use of auranofin, an oral gold preparation, in a 50-year-old woman with rheumatoid arthritis resulted in diarrhea, abdominal tenderness, nausea, and vomiting, which persisted despite discontinuation of auranofin therapy. The presumptive diagnosis was gold-induced colitis and eosinophilia. Administration of cromolyn sodium provided relief. Although this complication may be rare, evolving bowel symptoms in patients receiving auranofin demand prompt attention.

Original languageEnglish (US)
Pages (from-to)142-144
Number of pages3
JournalMayo Clinic proceedings
Volume62
Issue number2
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Medicine(all)

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