Atrial fibrillation and stroke - Increasing stroke risk with intervention

Christopher V. DeSimone, Malini Madhavan, Elisa Ebrille, Alejandro A. Rabinstein, Paul A. Friedman, Samuel J. Asirvatham

Research output: Contribution to journalReview articlepeer-review


In this review, we focus on the important newly recognized appreciation for the paradoxical increase in stroke and TIA as a result of intervention meant to treat atrial fibrillation (AF) with the hope of decreasing stroke risk in the long term. The impact of silent cerebral lesions recently appreciated as a potentially major limitation and risk with AF ablation is explained. We categorize our present understanding of how we can minimize risk and provide a platform for what will undoubtedly be newer study, changes in the way procedures are done today, and possibly vascular-based stroke-reduction strategies.

Original languageEnglish (US)
Pages (from-to)74-80
Number of pages7
JournalJournal of Atrial Fibrillation
Issue number4
StatePublished - Dec 1 2013


  • Ablation
  • Atrial fibrillation
  • Catheter
  • Embolism
  • Silent cerebral lesions

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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