Atherosclerotic renal artery stenosis: How big is the problem, and what happens if nothing is done?

Research output: Contribution to journalReview article

10 Scopus citations


Renal artery stenosis is a common problem, particularly for patients with other manifestations of atherosclerosis. Wide practice variations are apparent regarding how best to manage this disorder. Part of this variation is based on a broad range of clinical presentation, from incidentally identified disease of no clinical importance to rapidly progressive hypertension, renal failure, and refractory congestive heart failure. Advances in antihypertensive therapy, particularly as a result of angiotensin-converting enzyme inhibition and angiotensin receptor blockade, have led to improved blood pressure control and delayed recognition of renal artery disease. As a result, patients now sent for revascularization are older than before and have high comorbid disease risk, primarily related to cardiovascular events. Clinicians need to be vigilant for evidence of unsuspected renal artery stenosis as a cause of treatment-resistant hypertension and/or renal failure. Renal revascularization should be considered in viable individuals before the development of advanced renal insufficiency.

Original languageEnglish (US)
Pages (from-to)S5-S13
JournalJournal of hypertension
Issue numberSUPPL. 3
StatePublished - Oct 2005


  • Angiotensin-converting enzyme inhibitor
  • Renal artery angioplasty
  • Renal artery stenosis
  • Renovascular hypertension

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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