TY - JOUR
T1 - Atherosclerosis in the Back Yard
AU - Herrmann, Joerg
AU - Lerman, Amir
N1 - Funding Information:
Supported by grants from the National Institutes of Health (R01s HL63911, K24 HL69840-01-) and the Mayo Foundation.
PY - 2007/5/29
Y1 - 2007/5/29
N2 - The phenomenon of neovascularization in atherosclerosis has been widely recognized through "the eyes of novel imaging techniques" in recent years. Oxidative stress, inflammation, and hypoxia have been implied as the underlying mechanisms. The pathophysiologic consequences and therapeutic implications of this neovascularization process for atherosclerosis have, however, remained challenging and controversial. In the current focus issue of the Journal, 4 articles and this commentary are devoted to this topic.
AB - The phenomenon of neovascularization in atherosclerosis has been widely recognized through "the eyes of novel imaging techniques" in recent years. Oxidative stress, inflammation, and hypoxia have been implied as the underlying mechanisms. The pathophysiologic consequences and therapeutic implications of this neovascularization process for atherosclerosis have, however, remained challenging and controversial. In the current focus issue of the Journal, 4 articles and this commentary are devoted to this topic.
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U2 - 10.1016/j.jacc.2007.02.042
DO - 10.1016/j.jacc.2007.02.042
M3 - Review article
C2 - 17531659
AN - SCOPUS:34248682395
SN - 0735-1097
VL - 49
SP - 2102
EP - 2104
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 21
ER -