Athermal nerve sparing robot-assisted radical prostatectomy: Initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent

Rafael Nunez-Nateras, Kimberly J. Hurd, Erin N. Ferrigni, Erik P Castle, Paul E. Andrews, Mitchell R Humphreys

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: Microporous polysaccharide hemospheres (MPH) are hemostatic beads engineered from plant starch to accelerate the natural clotting cascade. The purpose of this report is to detail our initial experience with MPH as a topical hemostatic agent during robot-assisted radical prostatectomy (RARP). Methods: We examined a single surgeon series of 30 consecutive RARP's dividing patients into MPH or non-MPH groups. The last ten procedures utilized the MPH, which were matched 1:2 to non-MPH procedures for comparison. Nerve-sparing procedures were performed when clinically indicated and all done athermally. All demographic data, length of operation, margin status, blood loss, change in hemoglobin, and need for blood transfusion were prospectively collected and analyzed. Results: The baseline characteristics were the same. The post-operative decrease in hemoglobin was less in the MPH group (1.8 g/dL MPH group vs. 3.2 g/dL non-MPH). One patient in each group required a blood transfusion. Conclusions: These preliminary findings support the role for MPH as a potential hemostatic agent during athermal nerve-sparing RARP.

Original languageEnglish (US)
Pages (from-to)523-527
Number of pages5
JournalWorld Journal of Urology
Volume31
Issue number3
DOIs
StatePublished - Jun 2013

Fingerprint

Hemostatics
Prostatectomy
Polysaccharides
Blood Transfusion
Hemoglobins
Starch
Demography

Keywords

  • Microporous polysaccharide hemospheres
  • Robot-assisted radical prostatectomy
  • Topical hemostatic agent

ASJC Scopus subject areas

  • Urology

Cite this

Athermal nerve sparing robot-assisted radical prostatectomy : Initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent. / Nunez-Nateras, Rafael; Hurd, Kimberly J.; Ferrigni, Erin N.; Castle, Erik P; Andrews, Paul E.; Humphreys, Mitchell R.

In: World Journal of Urology, Vol. 31, No. 3, 06.2013, p. 523-527.

Research output: Contribution to journalArticle

@article{b46afc863c9d4a1faece07bfb8051776,
title = "Athermal nerve sparing robot-assisted radical prostatectomy: Initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent",
abstract = "Purpose: Microporous polysaccharide hemospheres (MPH) are hemostatic beads engineered from plant starch to accelerate the natural clotting cascade. The purpose of this report is to detail our initial experience with MPH as a topical hemostatic agent during robot-assisted radical prostatectomy (RARP). Methods: We examined a single surgeon series of 30 consecutive RARP's dividing patients into MPH or non-MPH groups. The last ten procedures utilized the MPH, which were matched 1:2 to non-MPH procedures for comparison. Nerve-sparing procedures were performed when clinically indicated and all done athermally. All demographic data, length of operation, margin status, blood loss, change in hemoglobin, and need for blood transfusion were prospectively collected and analyzed. Results: The baseline characteristics were the same. The post-operative decrease in hemoglobin was less in the MPH group (1.8 g/dL MPH group vs. 3.2 g/dL non-MPH). One patient in each group required a blood transfusion. Conclusions: These preliminary findings support the role for MPH as a potential hemostatic agent during athermal nerve-sparing RARP.",
keywords = "Microporous polysaccharide hemospheres, Robot-assisted radical prostatectomy, Topical hemostatic agent",
author = "Rafael Nunez-Nateras and Hurd, {Kimberly J.} and Ferrigni, {Erin N.} and Castle, {Erik P} and Andrews, {Paul E.} and Humphreys, {Mitchell R}",
year = "2013",
month = "6",
doi = "10.1007/s00345-011-0815-8",
language = "English (US)",
volume = "31",
pages = "523--527",
journal = "World Journal of Urology",
issn = "0724-4983",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Athermal nerve sparing robot-assisted radical prostatectomy

T2 - Initial experience with microporous polysaccharide hemospheres as a topical hemostatic agent

AU - Nunez-Nateras, Rafael

AU - Hurd, Kimberly J.

AU - Ferrigni, Erin N.

AU - Castle, Erik P

AU - Andrews, Paul E.

AU - Humphreys, Mitchell R

PY - 2013/6

Y1 - 2013/6

N2 - Purpose: Microporous polysaccharide hemospheres (MPH) are hemostatic beads engineered from plant starch to accelerate the natural clotting cascade. The purpose of this report is to detail our initial experience with MPH as a topical hemostatic agent during robot-assisted radical prostatectomy (RARP). Methods: We examined a single surgeon series of 30 consecutive RARP's dividing patients into MPH or non-MPH groups. The last ten procedures utilized the MPH, which were matched 1:2 to non-MPH procedures for comparison. Nerve-sparing procedures were performed when clinically indicated and all done athermally. All demographic data, length of operation, margin status, blood loss, change in hemoglobin, and need for blood transfusion were prospectively collected and analyzed. Results: The baseline characteristics were the same. The post-operative decrease in hemoglobin was less in the MPH group (1.8 g/dL MPH group vs. 3.2 g/dL non-MPH). One patient in each group required a blood transfusion. Conclusions: These preliminary findings support the role for MPH as a potential hemostatic agent during athermal nerve-sparing RARP.

AB - Purpose: Microporous polysaccharide hemospheres (MPH) are hemostatic beads engineered from plant starch to accelerate the natural clotting cascade. The purpose of this report is to detail our initial experience with MPH as a topical hemostatic agent during robot-assisted radical prostatectomy (RARP). Methods: We examined a single surgeon series of 30 consecutive RARP's dividing patients into MPH or non-MPH groups. The last ten procedures utilized the MPH, which were matched 1:2 to non-MPH procedures for comparison. Nerve-sparing procedures were performed when clinically indicated and all done athermally. All demographic data, length of operation, margin status, blood loss, change in hemoglobin, and need for blood transfusion were prospectively collected and analyzed. Results: The baseline characteristics were the same. The post-operative decrease in hemoglobin was less in the MPH group (1.8 g/dL MPH group vs. 3.2 g/dL non-MPH). One patient in each group required a blood transfusion. Conclusions: These preliminary findings support the role for MPH as a potential hemostatic agent during athermal nerve-sparing RARP.

KW - Microporous polysaccharide hemospheres

KW - Robot-assisted radical prostatectomy

KW - Topical hemostatic agent

UR - http://www.scopus.com/inward/record.url?scp=84878215314&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878215314&partnerID=8YFLogxK

U2 - 10.1007/s00345-011-0815-8

DO - 10.1007/s00345-011-0815-8

M3 - Article

C2 - 22198725

AN - SCOPUS:84878215314

VL - 31

SP - 523

EP - 527

JO - World Journal of Urology

JF - World Journal of Urology

SN - 0724-4983

IS - 3

ER -