At long last: Fatal Forty DDI: Ziprasidone, moxifloxacin, CYP3A4, CYP2D6, QT-prolongation

Kristen B. McCullough; Wayne T. Nicholson

doi:10.1007/978-1-4614-7495-1_181

At long last: Fatal Forty DDI: Ziprasidone, moxifloxacin, CYP3A4, CYP2D6, QT-prolongation

Kristen B. McCullough, Wayne T. Nicholson

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses two separate drug-drug interactions. There is a pharmacokinetic interaction between fluoxetine and cylcobenzaprine and a pharmacodynamic interaction with droperidol. The drug interactions are compounded by an electrolyte imbalance, resulting in prolongation of the QTc.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	807-811
Number of pages	5
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_181
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_181

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At long last: Fatal Forty DDI: Ziprasidone, moxifloxacin, CYP3A4, CYP2D6, QT-prolongation

Abstract

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