Asymmetric angioneurotic Edema associated with thrombolysis for acute stroke

A. Pancioli, T. Brott, V. Donaldson, R. Miller

Research output: Contribution to journalArticle

38 Scopus citations


We present a case of acute asymmetric angioneurotic edema associated with the use of recombinant tissue plasminogen activator (rtPA) for acute ischemic stroke. rtPA was administered for an acute ischemic stroke in accordance with the recently reported National Institute of Neurological Disorders and Stroke protocol, after which marked asymmetric angioedema requiring upper-airway control developed. Although atypical and anaphylactoid reactions have been reported with the use of rtPA for acute myocardial infarction, to our knowledge this is the first case report of asymmetric angioedema associated with the use of rtPA for acute ischemic stroke.

Original languageEnglish (US)
Pages (from-to)227-229
Number of pages3
JournalAnnals of emergency medicine
Issue number2
StatePublished - Jan 1 1997


ASJC Scopus subject areas

  • Emergency Medicine

Cite this