Abstract
Objective. To explore the role of smoking and obesity in primary Sjögren syndrome (pSS). Methods. Olmsted County (Minnesota, USA) residents (n = 106) diagnosed with pSS from 2000 to 2015 were compared to 3 controls without pSS and matched for age and sex who were randomly selected from Olmsted County residents. Results. Current smokers were less likely to be pSS cases (OR 0.34, 95% CI 0.14-0.85), while there was no association between former smoking and case/control status (OR 1.27, 95% CI 0.80-2.03) compared to never smokers. Smoking status was not associated with antinuclear antibody, anti-SSA, anti-SSB, or rheumatoid factor positivity (p > 0.05). OR for obesity was 0.79 (95% CI 0.48-1.30). Conclusion. In this population-based study, current smoking was inversely associated with case/control status, while body mass index lacked any association.
Original language | English (US) |
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Pages (from-to) | 727-730 |
Number of pages | 4 |
Journal | Journal of Rheumatology |
Volume | 46 |
Issue number | 7 |
DOIs | |
State | Published - 2019 |
Keywords
- Epidemiology
- Obesity
- SjÖgren Syndrome
- Smoking
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology