Association of hematopoietic cell transplantation-specific comorbidity index with resource utilization after allogeneic transplantation

L. Decook, Y. H. Chang, James L Slack, D. Gastineau, J. Leis, P. Noel, Jeanne Palmer, Lisa Sproat, M. Sorror, Nandita D Khera

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Comorbidities affect clinical outcomes and costs in medicine. The hematopoietic cell transplantation (HCT)-specific comorbidity index (HCT-CI) predicts mortality risk after HCT. Its association with resource utilization (RU) is unknown. In this single-center, retrospective study, we examined the association of HCT-CI with RU (readmissions, length of hospital stay (LOS) and days out of hospital alive (Doha)) in first 100 days (n=328) and 1 year (n=226) in allogeneic HCT patients from January 2010 to June 2014. Age, disease risk, conditioning and use of antithymocyte globulin were significantly different in the four groups with HCT-CI 0 to1 (n=138), 2 (n=56), 3 (n=55) or ' 3/44 (n=79). Although the readmissions were higher in the first 100 days for patients with HCT-CI >0-1 (P=0.03), they were not significantly different in patients over 1 year (P=0.13). In the multivariable analysis, patients with HCT-CI score of >0 to 1 had increased LOS and fewer Doha in both 100 days and 1 year after HCT. In this exploratory analysis, we found that HCT-CI >0 to 1 is associated with increased RU after allogeneic HCT. Recognizing predictors of RU can identify patients at risk of high utilization and help understand what drives health-care costs.

Original languageEnglish (US)
Pages (from-to)998-1002
Number of pages5
JournalBone Marrow Transplantation
Volume52
Issue number7
DOIs
StatePublished - Jul 1 2017

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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