Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43

K. Neiswanger; D. R. Stanford; R. S. Sparkes; D. Nishimura; T. Mohandas; I. Klisak; C. Heinzmann; E. D. Wieben

doi:10.1016/0888-7543(90)90192-W

Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43

K. Neiswanger, D. R. Stanford, R. S. Sparkes, D. Nishimura, T. Mohandas, I. Klisak, C. Heinzmann, E. D. Wieben

Biochemistry and Molecular Biology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Small nuclear ribonucleoproteins (snRNPs), which are composed of various U RNAs and several proteins, are components of the mRNA splicing apparatus. The snRNP protein E is encoded by a multigene family which consists of a single expressed gene and several processed pseudogenes. We have used somatic cell hybridization, in situ hybridization, and linkage analysis to both physically and genetically map the expressed E protein gene to human chromosome 1q25-43, with the most probable location being band 1q32. In addition to the snRNP E protein gene, two other snRNP components-the U1 RNA true multigene family and a group of class I U1 pseudogenes-are located on human chromosome 1.

Original language	English (US)
Pages (from-to)	503-508
Number of pages	6
Journal	Genomics
Volume	7
Issue number	4
DOIs	https://doi.org/10.1016/0888-7543(90)90192-W
State	Published - Aug 1990

ASJC Scopus subject areas

Genetics

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title = "Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43",

abstract = "Small nuclear ribonucleoproteins (snRNPs), which are composed of various U RNAs and several proteins, are components of the mRNA splicing apparatus. The snRNP protein E is encoded by a multigene family which consists of a single expressed gene and several processed pseudogenes. We have used somatic cell hybridization, in situ hybridization, and linkage analysis to both physically and genetically map the expressed E protein gene to human chromosome 1q25-43, with the most probable location being band 1q32. In addition to the snRNP E protein gene, two other snRNP components-the U1 RNA true multigene family and a group of class I U1 pseudogenes-are located on human chromosome 1.",

author = "K. Neiswanger and Stanford, {D. R.} and Sparkes, {R. S.} and D. Nishimura and T. Mohandas and I. Klisak and C. Heinzmann and Wieben, {E. D.}",

year = "1990",

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language = "English (US)",

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T1 - Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43

AU - Neiswanger, K.

AU - Stanford, D. R.

AU - Sparkes, R. S.

AU - Nishimura, D.

AU - Mohandas, T.

AU - Klisak, I.

AU - Heinzmann, C.

AU - Wieben, E. D.

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AB - Small nuclear ribonucleoproteins (snRNPs), which are composed of various U RNAs and several proteins, are components of the mRNA splicing apparatus. The snRNP protein E is encoded by a multigene family which consists of a single expressed gene and several processed pseudogenes. We have used somatic cell hybridization, in situ hybridization, and linkage analysis to both physically and genetically map the expressed E protein gene to human chromosome 1q25-43, with the most probable location being band 1q32. In addition to the snRNP E protein gene, two other snRNP components-the U1 RNA true multigene family and a group of class I U1 pseudogenes-are located on human chromosome 1.

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