Abstract
Small nuclear ribonucleoproteins (snRNPs), which are composed of various U RNAs and several proteins, are components of the mRNA splicing apparatus. The snRNP protein E is encoded by a multigene family which consists of a single expressed gene and several processed pseudogenes. We have used somatic cell hybridization, in situ hybridization, and linkage analysis to both physically and genetically map the expressed E protein gene to human chromosome 1q25-43, with the most probable location being band 1q32. In addition to the snRNP E protein gene, two other snRNP components-the U1 RNA true multigene family and a group of class I U1 pseudogenes-are located on human chromosome 1.
Original language | English (US) |
---|---|
Pages (from-to) | 503-508 |
Number of pages | 6 |
Journal | Genomics |
Volume | 7 |
Issue number | 4 |
DOIs | |
State | Published - Aug 1990 |
ASJC Scopus subject areas
- Genetics