Abstract
Small nuclear ribonucleoproteins (snRNPs), which are composed of various U RNAs and several proteins, are components of the mRNA splicing apparatus. The snRNP protein E is encoded by a multigene family which consists of a single expressed gene and several processed pseudogenes. We have used somatic cell hybridization, in situ hybridization, and linkage analysis to both physically and genetically map the expressed E protein gene to human chromosome 1q25-43, with the most probable location being band 1q32. In addition to the snRNP E protein gene, two other snRNP components-the U1 RNA true multigene family and a group of class I U1 pseudogenes-are located on human chromosome 1.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 503-508 |
| Number of pages | 6 |
| Journal | Genomics |
| Volume | 7 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 1990 |
ASJC Scopus subject areas
- Genetics
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Neiswanger, K., Stanford, D. R., Sparkes, R. S., Nishimura, D., Mohandas, T., Klisak, I., Heinzmann, C., & Wieben, E. D. (1990). Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43. Genomics, 7(4), 503-508. https://doi.org/10.1016/0888-7543(90)90192-W