Assessment of thermal tissue ablation with MR elastography

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Abstract

An important part of thermal ablation therapy is the assessment of the spatial extent of tissue coagulation. In this work, the mechanical properties of thermally-ablated tissue were quantitatively evaluated using magnetic resonance elastography (MRE). This study shows that the mechanical properties of focused ultrasound ablated tissue are significantly different from normal tissue, and the difference can be imaged and measured using MRE. Repeated experiments revealed a reproducible pattern of tissue mechanical property change during thermal ablation in ex vivo bovine muscle. This pattern may reflect changes in intrinsic tissue structure and could be used to evaluate tissue coagulation during thermal ablation therapy.

Original languageEnglish (US)
Pages (from-to)80-87
Number of pages8
JournalMagnetic Resonance in Medicine
Volume45
Issue number1
DOIs
StatePublished - Jan 20 2001

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Keywords

  • Elastography
  • Focused ultrasound
  • Magnetic resonance
  • Thermal ablation
  • Thermal effect

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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