Assessment of small bowel Crohn disease: Noninvasive peroral CT enterography compared with other imaging methods and endoscopy-feasibility study

Peter B. Wold, Joel Garland Fletcher, C. Daniel Johnson, William J. Sandborn

Research output: Contribution to journalArticle

271 Citations (Scopus)

Abstract

A feasibility study was conducted to evaluate two biphasic computed tomographic (CT) enterography protocols, a noninvasive CT technique with water administered perorally and CT enteroclysis with methylcellulose administered through a nasojejunal tube, in 23 patients known or suspected to have Crohn disease. Results were compared with the results of fluoroscopic small bowel examination and terminal ileoscopy for the detection of active Crohn disease in the terminal ileum. Luminal distention did not differ significantly between the two CT protocols. Arterial phase imaging was noncontributory in 22 of 23 cases. The noninvasive peroral water CT enterography protocol had similar accuracy (12 of 15 cases, 80%) for enabling the detection of active Crohn disease in comparison with CT enteroclysis with nasojejunal tube (seven of eight, 88%) and fluoroscopic small bowel examination (17 of 23, 74%). No fistulas were missed with use of either CT technique. The authors conclude that noninvasive peroral portal venous phase CT enterography with use of water is an accurate and feasible technique for detecting active small bowel inflammation in patients with Crohn disease.

Original languageEnglish (US)
Pages (from-to)275-281
Number of pages7
JournalRadiology
Volume229
Issue number1
DOIs
StatePublished - Oct 1 2003

Fingerprint

Feasibility Studies
Crohn Disease
Endoscopy
Water
Methylcellulose
Ileum
Fistula
Inflammation

Keywords

  • Comparative studies
  • Contrast media
  • Crohn disease
  • CT
  • Enteritis
  • Ileum
  • Intestines

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Assessment of small bowel Crohn disease : Noninvasive peroral CT enterography compared with other imaging methods and endoscopy-feasibility study. / Wold, Peter B.; Fletcher, Joel Garland; Johnson, C. Daniel; Sandborn, William J.

In: Radiology, Vol. 229, No. 1, 01.10.2003, p. 275-281.

Research output: Contribution to journalArticle

@article{002ceae3a19c477ebe41adb977a7600e,
title = "Assessment of small bowel Crohn disease: Noninvasive peroral CT enterography compared with other imaging methods and endoscopy-feasibility study",
abstract = "A feasibility study was conducted to evaluate two biphasic computed tomographic (CT) enterography protocols, a noninvasive CT technique with water administered perorally and CT enteroclysis with methylcellulose administered through a nasojejunal tube, in 23 patients known or suspected to have Crohn disease. Results were compared with the results of fluoroscopic small bowel examination and terminal ileoscopy for the detection of active Crohn disease in the terminal ileum. Luminal distention did not differ significantly between the two CT protocols. Arterial phase imaging was noncontributory in 22 of 23 cases. The noninvasive peroral water CT enterography protocol had similar accuracy (12 of 15 cases, 80{\%}) for enabling the detection of active Crohn disease in comparison with CT enteroclysis with nasojejunal tube (seven of eight, 88{\%}) and fluoroscopic small bowel examination (17 of 23, 74{\%}). No fistulas were missed with use of either CT technique. The authors conclude that noninvasive peroral portal venous phase CT enterography with use of water is an accurate and feasible technique for detecting active small bowel inflammation in patients with Crohn disease.",
keywords = "Comparative studies, Contrast media, Crohn disease, CT, Enteritis, Ileum, Intestines",
author = "Wold, {Peter B.} and Fletcher, {Joel Garland} and Johnson, {C. Daniel} and Sandborn, {William J.}",
year = "2003",
month = "10",
day = "1",
doi = "10.1148/radiol.2291020877",
language = "English (US)",
volume = "229",
pages = "275--281",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "1",

}

TY - JOUR

T1 - Assessment of small bowel Crohn disease

T2 - Noninvasive peroral CT enterography compared with other imaging methods and endoscopy-feasibility study

AU - Wold, Peter B.

AU - Fletcher, Joel Garland

AU - Johnson, C. Daniel

AU - Sandborn, William J.

PY - 2003/10/1

Y1 - 2003/10/1

N2 - A feasibility study was conducted to evaluate two biphasic computed tomographic (CT) enterography protocols, a noninvasive CT technique with water administered perorally and CT enteroclysis with methylcellulose administered through a nasojejunal tube, in 23 patients known or suspected to have Crohn disease. Results were compared with the results of fluoroscopic small bowel examination and terminal ileoscopy for the detection of active Crohn disease in the terminal ileum. Luminal distention did not differ significantly between the two CT protocols. Arterial phase imaging was noncontributory in 22 of 23 cases. The noninvasive peroral water CT enterography protocol had similar accuracy (12 of 15 cases, 80%) for enabling the detection of active Crohn disease in comparison with CT enteroclysis with nasojejunal tube (seven of eight, 88%) and fluoroscopic small bowel examination (17 of 23, 74%). No fistulas were missed with use of either CT technique. The authors conclude that noninvasive peroral portal venous phase CT enterography with use of water is an accurate and feasible technique for detecting active small bowel inflammation in patients with Crohn disease.

AB - A feasibility study was conducted to evaluate two biphasic computed tomographic (CT) enterography protocols, a noninvasive CT technique with water administered perorally and CT enteroclysis with methylcellulose administered through a nasojejunal tube, in 23 patients known or suspected to have Crohn disease. Results were compared with the results of fluoroscopic small bowel examination and terminal ileoscopy for the detection of active Crohn disease in the terminal ileum. Luminal distention did not differ significantly between the two CT protocols. Arterial phase imaging was noncontributory in 22 of 23 cases. The noninvasive peroral water CT enterography protocol had similar accuracy (12 of 15 cases, 80%) for enabling the detection of active Crohn disease in comparison with CT enteroclysis with nasojejunal tube (seven of eight, 88%) and fluoroscopic small bowel examination (17 of 23, 74%). No fistulas were missed with use of either CT technique. The authors conclude that noninvasive peroral portal venous phase CT enterography with use of water is an accurate and feasible technique for detecting active small bowel inflammation in patients with Crohn disease.

KW - Comparative studies

KW - Contrast media

KW - Crohn disease

KW - CT

KW - Enteritis

KW - Ileum

KW - Intestines

UR - http://www.scopus.com/inward/record.url?scp=0141741401&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141741401&partnerID=8YFLogxK

U2 - 10.1148/radiol.2291020877

DO - 10.1148/radiol.2291020877

M3 - Article

C2 - 12944602

AN - SCOPUS:0141741401

VL - 229

SP - 275

EP - 281

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 1

ER -