Assessment of nerve regeneration and adaptation after median nerve reconnection and digital neurovascular flap transfer

Peter J Dyck, E. H. Lambert, M. B. Wood, R. L. Linscheid

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Six patients with median severance (five sutured) were studied after an interval of 1.8 to 35 years to assess residual neurologic dificit, misdirected axonal regrowth, and adaptation to faulty reinnervation. Mild motor impairment was confirmed by the smaller thenar muscle action potentials and isometric muscle twitches from supramaximal stimulation of the median nerve. Sensory impairment was supported by the increased thresholds of vibratory (p = 0.003) and touch-pressure (p = 0.004) detection thresholds of the pulp of index fingers and decreased amplitudes of sensory nerve action potentials. A tactile hemidigit localization test revealed that localization was not significantly different from that on the contralateral side but perceptual territory was increased. This increase is best explained by misdirected axon regrowth without CNS adaptation. Long-standing faulty tactile digit localization in neurovascular skin flaps from finger to thumb also was demonstrated - further evidence that CNS adaptation in imperfect when sensory nerves to digits are relocated.

Original languageEnglish (US)
Pages (from-to)1586-1591
Number of pages6
JournalNeurology
Volume38
Issue number10
StatePublished - 1988

Fingerprint

Nerve Regeneration
Median Nerve
Touch
Action Potentials
Fingers
Muscles
Thumb
Nervous System
Axons
Pressure
Skin

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Assessment of nerve regeneration and adaptation after median nerve reconnection and digital neurovascular flap transfer. / Dyck, Peter J; Lambert, E. H.; Wood, M. B.; Linscheid, R. L.

In: Neurology, Vol. 38, No. 10, 1988, p. 1586-1591.

Research output: Contribution to journalArticle

Dyck, Peter J ; Lambert, E. H. ; Wood, M. B. ; Linscheid, R. L. / Assessment of nerve regeneration and adaptation after median nerve reconnection and digital neurovascular flap transfer. In: Neurology. 1988 ; Vol. 38, No. 10. pp. 1586-1591.
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