TY - JOUR
T1 - Assessment of myocardial perfusion during adenosine stress using real time three-dimensional and two-dimensional myocardial contrast echocardiography
T2 - Comparison with single-photon emission computed tomography
AU - Abdelmoneim, Sahar S.
AU - Bernier, Mathieu
AU - Dhoble, Abhijeet
AU - Moir, Stuart
AU - Hagen, Mary E.
AU - Ness, Sue Ann C.
AU - Abdel-Kader, Samir S.
AU - Pellikka, Patricia A.
AU - Mulvagh, Sharon L.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2010/4
Y1 - 2010/4
N2 - Objectives: To evaluate diagnostic accuracy of adenosine two-dimensional and three-dimensional myocardial contrast echocardiography (2D- and 3D-MCE) compared with single-photon emission computed tomography (SPECT) for assessing myocardial perfusion. Methods: From January through August 2007, patients with known or suspected CAD who were referred for SPECT underwent simultaneous adenosine 2D-MCE and 3D-MCE (live and full volume FV). Perfusion and wall motion in 17 segments in the left anterior descending, left circumflex, and right coronary artery territories were analyzed. Results: We studied 30 patients: mean (SD) age, 72.6 (8.2) years; 19 (63%) men. Perfusion by SPECT was abnormal in 13 patients (43%). When comparing MCE with SPECT, sensitivity was comparable for 2D-MCE, 92%; live 3D-MCE, 91%; and FV 3D-MCE, 90%. Specificity was comparable for 2D-MCE, 75%; live 3D-MCE, 69%; and FV 3D-MCE, 79%. Agreement between live 3D-MCE and 2D-MCE was 92% (κSE, 0.83 0.17) and between FV 3D-MCE and 2D-MCE, 88% (κSE, 0.76 0.13). For eight patients in whom SPECT showed reversible defects, live 3D-MCE correctly identified defects in seven (88%), whereas FV 3D-MCE correctly identified them in five (63%) (P = 0.57). Conclusion: Myocardial perfusion assessment is feasible by 3D-MCE with the advantage of rapid, facile acquisition and offline image manipulation. (Echocardiography 2010;27:421-429)
AB - Objectives: To evaluate diagnostic accuracy of adenosine two-dimensional and three-dimensional myocardial contrast echocardiography (2D- and 3D-MCE) compared with single-photon emission computed tomography (SPECT) for assessing myocardial perfusion. Methods: From January through August 2007, patients with known or suspected CAD who were referred for SPECT underwent simultaneous adenosine 2D-MCE and 3D-MCE (live and full volume FV). Perfusion and wall motion in 17 segments in the left anterior descending, left circumflex, and right coronary artery territories were analyzed. Results: We studied 30 patients: mean (SD) age, 72.6 (8.2) years; 19 (63%) men. Perfusion by SPECT was abnormal in 13 patients (43%). When comparing MCE with SPECT, sensitivity was comparable for 2D-MCE, 92%; live 3D-MCE, 91%; and FV 3D-MCE, 90%. Specificity was comparable for 2D-MCE, 75%; live 3D-MCE, 69%; and FV 3D-MCE, 79%. Agreement between live 3D-MCE and 2D-MCE was 92% (κSE, 0.83 0.17) and between FV 3D-MCE and 2D-MCE, 88% (κSE, 0.76 0.13). For eight patients in whom SPECT showed reversible defects, live 3D-MCE correctly identified defects in seven (88%), whereas FV 3D-MCE correctly identified them in five (63%) (P = 0.57). Conclusion: Myocardial perfusion assessment is feasible by 3D-MCE with the advantage of rapid, facile acquisition and offline image manipulation. (Echocardiography 2010;27:421-429)
KW - 3-dimensional echocardiography
KW - Contrast echocardiography
KW - Coronary artery disease
KW - Single-photon emission computed tomography
UR - http://www.scopus.com/inward/record.url?scp=77951218752&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951218752&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8175.2009.01026.x
DO - 10.1111/j.1540-8175.2009.01026.x
M3 - Article
C2 - 20331695
AN - SCOPUS:77951218752
SN - 0742-2822
VL - 27
SP - 421
EP - 429
JO - Echocardiography
JF - Echocardiography
IS - 4
ER -