TY - JOUR
T1 - Assessment of Myocardial Microvascular Function
T2 - New Opportunities in Fast Computed Tomography
AU - Daghini, Elena
AU - Lerman, Lilach O.
N1 - Funding Information:
This study was partly supported by National Institutes of Health grant HL-77131 and by the Universita' degli Studi di Pisa, Italy.
PY - 2007/1
Y1 - 2007/1
N2 - It has been increasingly recognized that the initial site of cardiac damage in several forms of cardiovascular disease resides in the microcirculation. Noninvasive or minimally invasive evaluation of myocardial microvascular functional attributes, such as myocardial perfusion or microvascular permeability, could be an invaluable tool in the clinical practice. Advances in the field of computed tomography over the past three decades culminated in the advent of fast scanners, which show promise to provide both fine cardiac anatomic detail and quantification of the function of the myocardial microcirculation. This review describes the approach and utility of measurements of myocardial microvascular function obtained with state-of-the-art cardiac computed tomography.
AB - It has been increasingly recognized that the initial site of cardiac damage in several forms of cardiovascular disease resides in the microcirculation. Noninvasive or minimally invasive evaluation of myocardial microvascular functional attributes, such as myocardial perfusion or microvascular permeability, could be an invaluable tool in the clinical practice. Advances in the field of computed tomography over the past three decades culminated in the advent of fast scanners, which show promise to provide both fine cardiac anatomic detail and quantification of the function of the myocardial microcirculation. This review describes the approach and utility of measurements of myocardial microvascular function obtained with state-of-the-art cardiac computed tomography.
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U2 - 10.1016/j.tcm.2006.10.002
DO - 10.1016/j.tcm.2006.10.002
M3 - Review article
C2 - 17210473
AN - SCOPUS:33845938235
SN - 1050-1738
VL - 17
SP - 14
EP - 19
JO - Trends in cardiovascular medicine
JF - Trends in cardiovascular medicine
IS - 1
ER -