Assessment of disease activity in large-vessel vasculitis: Results of an international delphi exercise

International Delphi on Disease Activity Assessment in Large-vessel Vasculitis

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Objective. To arrive at consensus for candidate outcomes for disease activity assessment in largevessel vasculitis (LVV) in clinical trials. Methods.A Delphi survey including 99 items was circulated among international experts for 3 rounds. Results. Fifty-seven items were accepted for both giant cell arteritis and Takayasu arteritis. Sixty-seven percent of experts voted to have a common approach for both diseases with additional disease-specific items such as weight loss, scalp tenderness/necrosis, morning stiffness, dizziness, visual symptoms, and imaging. Conclusion. This study highlights similarities and differences in experts' perspectives for assessing clinical activity in LVV and may guide a consensus-driven core set of validated outcomes.

Original languageEnglish (US)
Pages (from-to)1928-1932
Number of pages5
JournalJournal of Rheumatology
Volume44
Issue number12
DOIs
StatePublished - Dec 1 2017

Keywords

  • Giant cell arteritis
  • Large vessel
  • Outcomes
  • Takayasu arteritis
  • Vasculitis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    International Delphi on Disease Activity Assessment in Large-vessel Vasculitis (2017). Assessment of disease activity in large-vessel vasculitis: Results of an international delphi exercise. Journal of Rheumatology, 44(12), 1928-1932. https://doi.org/10.3899/jrheum.161269