Assessment and management of aortic valve disease in patients with left ventricular dysfunction

Mackram Eleid, Sunil Mankad, Paul Sorajja

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The onset of symptoms or left ventricular systolic dysfunction heralds a poor prognosis for patients with either aortic stenosis or aortic regurgitation. Echocardiography is the primary imaging modality for assessment of aortic valvular lesions. Cardiac catheterization is indicated to determine the severity of the aortic valve lesion when there is a discrepancy between the clinical findings and the results of echocardiography in patients with either symptoms or left ventricular dysfunction. For patients with low-gradient, low-output aortic stenosis, dobutamine provocation should be used to differentiate truly severe aortic stenosis from patients with a primary cardiomyopathy and low aortic valve area due to low forward flow. Aortic valve surgery improves myocardial performance by relief of ventricular afterload in both patients with severe stenosis and those with severe regurgitation. Surgery should be pursued in both patients with severe aortic stenosis and those with severe regurgitation regardless of the degree of left ventricular dysfunction.

Original languageEnglish (US)
Pages (from-to)1-14
Number of pages14
JournalHeart Failure Reviews
Volume18
Issue number1
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

Fingerprint

Aortic Diseases
Left Ventricular Dysfunction
Aortic Valve
Aortic Valve Stenosis
Echocardiography
Dobutamine
Aortic Valve Insufficiency
Cardiac Catheterization
Cardiomyopathies
Pathologic Constriction

Keywords

  • Aortic regurgitation
  • Aortic stenosis
  • Left ventricular dysfunction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Assessment and management of aortic valve disease in patients with left ventricular dysfunction. / Eleid, Mackram; Mankad, Sunil; Sorajja, Paul.

In: Heart Failure Reviews, Vol. 18, No. 1, 01.01.2013, p. 1-14.

Research output: Contribution to journalArticle

@article{6f4ae77d80d14c1bb162753771380246,
title = "Assessment and management of aortic valve disease in patients with left ventricular dysfunction",
abstract = "The onset of symptoms or left ventricular systolic dysfunction heralds a poor prognosis for patients with either aortic stenosis or aortic regurgitation. Echocardiography is the primary imaging modality for assessment of aortic valvular lesions. Cardiac catheterization is indicated to determine the severity of the aortic valve lesion when there is a discrepancy between the clinical findings and the results of echocardiography in patients with either symptoms or left ventricular dysfunction. For patients with low-gradient, low-output aortic stenosis, dobutamine provocation should be used to differentiate truly severe aortic stenosis from patients with a primary cardiomyopathy and low aortic valve area due to low forward flow. Aortic valve surgery improves myocardial performance by relief of ventricular afterload in both patients with severe stenosis and those with severe regurgitation. Surgery should be pursued in both patients with severe aortic stenosis and those with severe regurgitation regardless of the degree of left ventricular dysfunction.",
keywords = "Aortic regurgitation, Aortic stenosis, Left ventricular dysfunction",
author = "Mackram Eleid and Sunil Mankad and Paul Sorajja",
year = "2013",
month = "1",
day = "1",
doi = "10.1007/s10741-012-9311-5",
language = "English (US)",
volume = "18",
pages = "1--14",
journal = "Heart Failure Reviews",
issn = "1382-4147",
publisher = "Springer Netherlands",
number = "1",

}

TY - JOUR

T1 - Assessment and management of aortic valve disease in patients with left ventricular dysfunction

AU - Eleid, Mackram

AU - Mankad, Sunil

AU - Sorajja, Paul

PY - 2013/1/1

Y1 - 2013/1/1

N2 - The onset of symptoms or left ventricular systolic dysfunction heralds a poor prognosis for patients with either aortic stenosis or aortic regurgitation. Echocardiography is the primary imaging modality for assessment of aortic valvular lesions. Cardiac catheterization is indicated to determine the severity of the aortic valve lesion when there is a discrepancy between the clinical findings and the results of echocardiography in patients with either symptoms or left ventricular dysfunction. For patients with low-gradient, low-output aortic stenosis, dobutamine provocation should be used to differentiate truly severe aortic stenosis from patients with a primary cardiomyopathy and low aortic valve area due to low forward flow. Aortic valve surgery improves myocardial performance by relief of ventricular afterload in both patients with severe stenosis and those with severe regurgitation. Surgery should be pursued in both patients with severe aortic stenosis and those with severe regurgitation regardless of the degree of left ventricular dysfunction.

AB - The onset of symptoms or left ventricular systolic dysfunction heralds a poor prognosis for patients with either aortic stenosis or aortic regurgitation. Echocardiography is the primary imaging modality for assessment of aortic valvular lesions. Cardiac catheterization is indicated to determine the severity of the aortic valve lesion when there is a discrepancy between the clinical findings and the results of echocardiography in patients with either symptoms or left ventricular dysfunction. For patients with low-gradient, low-output aortic stenosis, dobutamine provocation should be used to differentiate truly severe aortic stenosis from patients with a primary cardiomyopathy and low aortic valve area due to low forward flow. Aortic valve surgery improves myocardial performance by relief of ventricular afterload in both patients with severe stenosis and those with severe regurgitation. Surgery should be pursued in both patients with severe aortic stenosis and those with severe regurgitation regardless of the degree of left ventricular dysfunction.

KW - Aortic regurgitation

KW - Aortic stenosis

KW - Left ventricular dysfunction

UR - http://www.scopus.com/inward/record.url?scp=84871989150&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871989150&partnerID=8YFLogxK

U2 - 10.1007/s10741-012-9311-5

DO - 10.1007/s10741-012-9311-5

M3 - Article

C2 - 22434219

AN - SCOPUS:84871989150

VL - 18

SP - 1

EP - 14

JO - Heart Failure Reviews

JF - Heart Failure Reviews

SN - 1382-4147

IS - 1

ER -