Assessing individual cardiac risk using extra-cardiac arterial imaging

Matthew R. Nelson, R. Todd Hurst, Farouk Mookadam

Research output: Contribution to journalReview articlepeer-review


Cardiovascular disease is the leading cause of death globally. Cardiovascular risk factors predict the risk of cardiovascular events in populations but have limitations in predicting individual risk. Emerging technologies that non-invasively measure carotid intima media thickness, aortic pressure and brachial artery reactivity may be useful in identifying the vulnerable patient who may benefit from more aggressive preventive therapy. These tests vary between each other in their reproducibility, cost, required operator skill, availability and patient preparation. However, all require further validation for clinical use as screening tests for cardiovascular disease.

Original languageEnglish (US)
Pages (from-to)529-543
Number of pages15
JournalExpert Review of Cardiovascular Therapy
Issue number4
StatePublished - Apr 1 2010


  • Applanation tonometry
  • Brachial artery flow-mediated dilatation
  • Cardiovascular risk
  • Carotid intima media thickness

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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