Aspiration-related pulmonary syndromes

Xiaowen Hu, Joyce S. Lee, Paolo T. Pianosi, Jay H Ryu

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Aspiration of foreign matter into the airways and lungs can cause a wide spectrum of pulmonary disorders with various presentations. The type of syndrome resulting from aspiration depends on the quantity and nature of the aspirated material, the chronicity, and the host responses. Aspiration is most likely to occur in subjects with a decreased level of consciousness, compromised airway defense mechanisms, dysphagia, gastroesophageal reflux, and recurrent vomiting. These aspiration-related syndromes can be categorized into airway disorders, including vocal cord dysfunction, large airway obstruction with a foreign body, bronchiectasis, bronchoconstriction, and diffuse aspiration bronchiolitis, or parenchymal disorders, including aspiration pneumonitis, aspiration pneumonia, and exogenous lipoid pneumonia. In idiopathic pulmonary fibrosis, aspiration has been implicated in disease progression and acute exacerbation. Aspiration may increase the risk of bronchiolitis obliterans syndrome in patients who have undergone a lung transplant. Accumulating evidence suggests that a causative role for aspiration is often unsuspected in patients presenting with aspiration-related pulmonary diseases; thus, many cases go undiagnosed. Herein, we discuss the broadening spectrum of these pulmonary syndromes with a focus on presenting features and diagnostic aspects.

Original languageEnglish (US)
Pages (from-to)815-823
Number of pages9
JournalChest
Volume147
Issue number3
DOIs
StatePublished - Mar 1 2015

Fingerprint

Lung
Pneumonia
Vocal Cord Dysfunction
Aspirations (Psychology)
Bronchiolitis Obliterans
Aspiration Pneumonia
Idiopathic Pulmonary Fibrosis
Bronchiolitis
Bronchiectasis
Bronchoconstriction
Airway Obstruction
Defense Mechanisms
Deglutition Disorders
Gastroesophageal Reflux
Foreign Bodies
Consciousness
Lung Diseases
Vomiting
Disease Progression
Transplants

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Hu, X., Lee, J. S., Pianosi, P. T., & Ryu, J. H. (2015). Aspiration-related pulmonary syndromes. Chest, 147(3), 815-823. https://doi.org/10.1378/chest.14-1049

Aspiration-related pulmonary syndromes. / Hu, Xiaowen; Lee, Joyce S.; Pianosi, Paolo T.; Ryu, Jay H.

In: Chest, Vol. 147, No. 3, 01.03.2015, p. 815-823.

Research output: Contribution to journalArticle

Hu, X, Lee, JS, Pianosi, PT & Ryu, JH 2015, 'Aspiration-related pulmonary syndromes', Chest, vol. 147, no. 3, pp. 815-823. https://doi.org/10.1378/chest.14-1049
Hu, Xiaowen ; Lee, Joyce S. ; Pianosi, Paolo T. ; Ryu, Jay H. / Aspiration-related pulmonary syndromes. In: Chest. 2015 ; Vol. 147, No. 3. pp. 815-823.
@article{b0941dc2da6d436ab4097faf81dfcde1,
title = "Aspiration-related pulmonary syndromes",
abstract = "Aspiration of foreign matter into the airways and lungs can cause a wide spectrum of pulmonary disorders with various presentations. The type of syndrome resulting from aspiration depends on the quantity and nature of the aspirated material, the chronicity, and the host responses. Aspiration is most likely to occur in subjects with a decreased level of consciousness, compromised airway defense mechanisms, dysphagia, gastroesophageal reflux, and recurrent vomiting. These aspiration-related syndromes can be categorized into airway disorders, including vocal cord dysfunction, large airway obstruction with a foreign body, bronchiectasis, bronchoconstriction, and diffuse aspiration bronchiolitis, or parenchymal disorders, including aspiration pneumonitis, aspiration pneumonia, and exogenous lipoid pneumonia. In idiopathic pulmonary fibrosis, aspiration has been implicated in disease progression and acute exacerbation. Aspiration may increase the risk of bronchiolitis obliterans syndrome in patients who have undergone a lung transplant. Accumulating evidence suggests that a causative role for aspiration is often unsuspected in patients presenting with aspiration-related pulmonary diseases; thus, many cases go undiagnosed. Herein, we discuss the broadening spectrum of these pulmonary syndromes with a focus on presenting features and diagnostic aspects.",
author = "Xiaowen Hu and Lee, {Joyce S.} and Pianosi, {Paolo T.} and Ryu, {Jay H}",
year = "2015",
month = "3",
day = "1",
doi = "10.1378/chest.14-1049",
language = "English (US)",
volume = "147",
pages = "815--823",
journal = "Chest",
issn = "0012-3692",
publisher = "American College of Chest Physicians",
number = "3",

}

TY - JOUR

T1 - Aspiration-related pulmonary syndromes

AU - Hu, Xiaowen

AU - Lee, Joyce S.

AU - Pianosi, Paolo T.

AU - Ryu, Jay H

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Aspiration of foreign matter into the airways and lungs can cause a wide spectrum of pulmonary disorders with various presentations. The type of syndrome resulting from aspiration depends on the quantity and nature of the aspirated material, the chronicity, and the host responses. Aspiration is most likely to occur in subjects with a decreased level of consciousness, compromised airway defense mechanisms, dysphagia, gastroesophageal reflux, and recurrent vomiting. These aspiration-related syndromes can be categorized into airway disorders, including vocal cord dysfunction, large airway obstruction with a foreign body, bronchiectasis, bronchoconstriction, and diffuse aspiration bronchiolitis, or parenchymal disorders, including aspiration pneumonitis, aspiration pneumonia, and exogenous lipoid pneumonia. In idiopathic pulmonary fibrosis, aspiration has been implicated in disease progression and acute exacerbation. Aspiration may increase the risk of bronchiolitis obliterans syndrome in patients who have undergone a lung transplant. Accumulating evidence suggests that a causative role for aspiration is often unsuspected in patients presenting with aspiration-related pulmonary diseases; thus, many cases go undiagnosed. Herein, we discuss the broadening spectrum of these pulmonary syndromes with a focus on presenting features and diagnostic aspects.

AB - Aspiration of foreign matter into the airways and lungs can cause a wide spectrum of pulmonary disorders with various presentations. The type of syndrome resulting from aspiration depends on the quantity and nature of the aspirated material, the chronicity, and the host responses. Aspiration is most likely to occur in subjects with a decreased level of consciousness, compromised airway defense mechanisms, dysphagia, gastroesophageal reflux, and recurrent vomiting. These aspiration-related syndromes can be categorized into airway disorders, including vocal cord dysfunction, large airway obstruction with a foreign body, bronchiectasis, bronchoconstriction, and diffuse aspiration bronchiolitis, or parenchymal disorders, including aspiration pneumonitis, aspiration pneumonia, and exogenous lipoid pneumonia. In idiopathic pulmonary fibrosis, aspiration has been implicated in disease progression and acute exacerbation. Aspiration may increase the risk of bronchiolitis obliterans syndrome in patients who have undergone a lung transplant. Accumulating evidence suggests that a causative role for aspiration is often unsuspected in patients presenting with aspiration-related pulmonary diseases; thus, many cases go undiagnosed. Herein, we discuss the broadening spectrum of these pulmonary syndromes with a focus on presenting features and diagnostic aspects.

UR - http://www.scopus.com/inward/record.url?scp=84924901788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84924901788&partnerID=8YFLogxK

U2 - 10.1378/chest.14-1049

DO - 10.1378/chest.14-1049

M3 - Article

C2 - 25732447

AN - SCOPUS:84924901788

VL - 147

SP - 815

EP - 823

JO - Chest

JF - Chest

SN - 0012-3692

IS - 3

ER -