Are high-sensitivity cardiac troponin I values stable between preoperative visit and day of non-cardiac surgery?

Eslam Samaha, Mohammad A. Helwani, Jamie C. Brown, Frank Brown, Allan S Jaffe, Mitchell G. Scott, Peter Nagele

Research output: Contribution to journalArticle

Abstract

Background It is unclear if cardiac troponin values are stable in patients prior to undergoing non-cardiac surgery, or if they tend to rise towards the day of surgery. Methods In this small pilot study (n = 18) among patients with cardiac risk undergoing non-cardiac surgery, we determined if high-sensitivity cardiac troponin I (hscTnI) changes between the preoperative clinic visit and the day of surgery. HscTnI was measured on an Abbott Architect STAT (Abbott Laboratories, USA) platform. Results The mean duration between preoperative clinic visit and day of surgery was 8.7 ± 2.8 (SD) days. Median hscTnI was 3.4 ng/L [2.0–4.8, IQR] at the preoperative visit and 2.8 ng/L [2.3–4.4] on the day of surgery (mean difference − 0.24 ng/L, 95% CI - 0.73 to 0.24 ng/L, p = 0.30). Only one patient had a large change (> 50%) along with symptoms. Discussion Evidence from this small study suggests that cardiac troponin values are stable in most high-risk patients, absent clinical events, within 10 days prior to non-cardiac surgery.

Original languageEnglish (US)
Pages (from-to)171-172
Number of pages2
JournalClinical Biochemistry
Volume52
DOIs
StatePublished - Feb 1 2018

ASJC Scopus subject areas

  • Clinical Biochemistry

Fingerprint Dive into the research topics of 'Are high-sensitivity cardiac troponin I values stable between preoperative visit and day of non-cardiac surgery?'. Together they form a unique fingerprint.

  • Cite this